Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies

K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications

AA D'souza, R Shegokar - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This
USFDA-approved polymer is popular due to its tunable properties and well-established …

Engineered nanoparticles for drug delivery in cancer therapy

T Sun, YS Zhang, B Pang, DC Hyun… - Nanomaterials and …, 2021 - taylorfrancis.com
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …

Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Biopolymer nano-particles and natural nano-carriers for nano-encapsulation of phenolic compounds

AF Esfanjani, SM Jafari - Colloids and Surfaces B: Biointerfaces, 2016 - Elsevier
Phenolic compounds are major micronutrients in our diet, 1 and evidence for their role in the
prevention of degenerative diseases such as cancer, inflammation and neurodegenerative …

Endogenous and exogenous stimuli-responsive drug delivery systems for programmed site-specific release

A Raza, T Rasheed, F Nabeel, U Hayat, M Bilal… - Molecules, 2019 - mdpi.com
In this study, we reviewed state-of-the-art endogenous-based and exogenous-based stimuli-
responsive drug delivery systems (DDS) for programmed site-specific release to overcome …

Nanomicelles: Types, properties and applications in drug delivery

A Bose, D Roy Burman, B Sikdar… - IET …, 2021 - Wiley Online Library
Nanomicelles are self‐assembling nanosized (usually with particle size within a range of 10
to 100 nm) colloidal dispersions with a hydrophobic core and hydrophilic shell. Owing to its …

Cleavable PEGylation: a strategy for overcoming the “PEG dilemma” in efficient drug delivery

Y Fang, J Xue, S Gao, A Lu, D Yang, H Jiang, Y He… - Drug Delivery, 2017 - Taylor & Francis
To prolong the circulation time of drug, PEGylation has been widely used via the enhanced
permeability and retention (EPR) effect, thereby providing new hope for better treatment …