COVID-19: Immunology and treatment options
S Felsenstein, JA Herbert, PS McNamara… - Clinical …, 2020 - Elsevier
The novel coronavirus SARS-CoV2 causes COVID-19, a pandemic threatening millions. As
protective immunity does not exist in humans and the virus is capable of esca** innate …
protective immunity does not exist in humans and the virus is capable of esca** innate …
Dengue vaccines: an update
Dengue is one of the most prevalent mosquito-borne diseases in the world, affecting an
estimated 390 million people each year, according to models. For the last two decades …
estimated 390 million people each year, according to models. For the last two decades …
[HTML][HTML] Modified mRNA vaccines protect against Zika virus infection
The emergence of ZIKV infection has prompted a global effort to develop safe and effective
vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine …
vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine …
Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border
Abstract Background In Colombia, the dengue virus (DENV) has been endemic for decades,
and with the recent entry of the chikungunya virus (CHIKV)(2014) and the Zika virus …
and with the recent entry of the chikungunya virus (CHIKV)(2014) and the Zika virus …
The antigenic structure of Zika virus and its relation to other flaviviruses: implications for infection and immunoprophylaxis
FX Heinz, K Stiasny - Microbiology and Molecular Biology …, 2017 - Am Soc Microbiol
Zika virus was discovered∼ 70 years ago in Uganda and maintained a low profile as a
human disease agent in Africa and Asia. Only recently has it caused explosive outbreaks in …
human disease agent in Africa and Asia. Only recently has it caused explosive outbreaks in …
Pathogenesis and virulence of flavivirus infections
The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge
J Wen, A Elong Ngono, JA Regla-Nava, K Kim… - Nature …, 2017 - nature.com
Zika virus (ZIKV) and dengue virus (DENV) are antigenically related flaviviruses that share
cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of …
cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of …
[HTML][HTML] Prior exposure to Zika virus significantly enhances peak dengue-2 viremia in rhesus macaques
Structural and functional homologies between the Zika and Dengue viruses' envelope
proteins raise the possibility that cross-reactive antibodies induced following Zika virus …
proteins raise the possibility that cross-reactive antibodies induced following Zika virus …
Dengue and Zika viruses: Epidemiological history, potential therapies, and promising vaccines
Dengue virus (DENV), which can lead to fatal hemorrhagic fever, affects 390 million people
worldwide. The closely related Zika virus (ZIKV) causes microcephaly in newborns and …
worldwide. The closely related Zika virus (ZIKV) causes microcephaly in newborns and …