Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders

MG Rahbardar… - Iranian journal of basic …, 2020‏ - pmc.ncbi.nlm.nih.gov
Rosemary (Rosmarinus officinalis L.) is an evergreen bushy shrub which grows along the
Mediterranean Sea, and sub-Himalayan areas. In folk medicine, it has been used as an …

Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases

NS Mohd Sairazi… - … Based Complementary and …, 2020‏ - Wiley Online Library
In recent years, natural products, which originate from plants, animals, and fungi, together
with their bioactive compounds have been intensively explored and studied for their …

Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology

S Kumar, DB Lombard - Critical reviews in biochemistry and …, 2018‏ - Taylor & Francis
Sirtuins are NAD+-dependent protein deacylases/ADP-ribosyltransferases that have
emerged as candidate targets for new therapeutics to treat metabolic disorders and other …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011‏ - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

[HTML][HTML] Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

J St-Pierre, S Drori, M Uldry, JM Silvaggi, J Rhee… - Cell, 2006‏ - cell.com
PPARγ coactivator 1α (PGC-1α) is a potent stimulator of mitochondrial biogenesis and
respiration. Since the mitochondrial electron transport chain is the main producer of reactive …

Emerging roles of SIRT5 in metabolism, cancer, and SARS-CoV-2 infection

E Fabbrizi, F Fiorentino, V Carafa, L Altucci, A Mai… - Cells, 2023‏ - mdpi.com
Sirtuin 5 (SIRT5) is a predominantly mitochondrial enzyme catalyzing the removal of glutaryl,
succinyl, malonyl, and acetyl groups from lysine residues through a NAD+-dependent …

Biosynthetic pathways to nonproteinogenic α-amino acids

JB Hedges, KS Ryan - Chemical Reviews, 2019‏ - ACS Publications
Natural nonproteinogenic amino acids vastly outnumber the well-known 22 proteinogenic
amino acids. Such amino acids are generated in specialized metabolic pathways. In these …

Cortical lesions in multiple sclerosis

M Calabrese, M Filippi, P Gallo - Nature Reviews Neurology, 2010‏ - nature.com
Multiple sclerosis (MS) is typically considered to be a chronic inflammatory–demyelinating
disease of CNS white matter. In the past decade, however, pathological and MRI studies …

Regional hippocampal atrophy in multiple sclerosis

NL Sicotte, KC Kern, BS Giesser, A Arshanapalli… - Brain, 2008‏ - academic.oup.com
Gray matter brain structures, including deep nuclei and the cerebral cortex, are affected
significantly and early in the course of multiple sclerosis and these changes may not be …

Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders

JW Phillis, LA Horrocks, AA Farooqui - Brain research reviews, 2006‏ - Elsevier
Three enzyme systems, cyclooxygenases that generate prostaglandins, lipoxygenases that
form hydroxy derivatives and leukotrienes, and epoxygenases that give rise to …