The recent outbreak of coronavirus disease 2019 (COVID-19) highlights an urgent need for
therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an …

Niclosamide is an oral antihelminthic drug used to treat parasitic infections in millions of
people worldwide. However recent studies have indicated that niclosamide may have broad …

The repositioning or “repurposing” of existing therapies for alternative disease indications is
an attractive approach that can save significant investments of time and money during drug …

Ischemic stroke (IS) is a multifactorial and heterogeneous neurological disorder with high
rate of death and long-term impairment. Despite years of studies, there are still no stroke …

Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …

Background Mitochondrial uncouplers are well-known for their ability to treat a myriad of
metabolic diseases, including obesity and fatty liver diseases. However, for many years now …

Ovarian cancer is the leading cause of death from gynecologic malignancy in the Western
world. This is due, in part, to the fact that despite standard treatment of surgery and …

Almost one decade ago, etoposide, doxorubicin, cisplatin and mitotane (EDP-M) has been
established as first-line systemic therapy of metastatic adrenocortical carcinoma (ACC) …

Simple Summary Despite the leaps and bounds in the prevention and treatment of cancer, it
remains the second leading cause of death worldwide. A significant hurdle during cancer …

Niclosamide is an anthelmintic drug that has been used for over 50 years mainly to treat
tapeworm infections. However, with the increase in drug repurposing initiatives, niclosamide …