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[HTML][HTML] Artificial intelligence in bone marrow histological diagnostics: potential applications and challenges
The expanding digitalization of routine diagnostic histological slides holds a potential to
apply artificial intelligence (AI) to pathology, including bone marrow (BM) histology. In this …
apply artificial intelligence (AI) to pathology, including bone marrow (BM) histology. In this …
Myeloproliferative neoplasms: Diagnostic workup of the cythemic patient
Elevated peripheral blood (PB) cell counts, such as leukocytosis, thrombocytosis, and
polycythemia, are often the presenting symptom in patients with myeloproliferative …
polycythemia, are often the presenting symptom in patients with myeloproliferative …
Inhibition of proinflammatory signaling impairs fibrosis of bone marrow mesenchymal stromal cells in myeloproliferative neoplasms
M Vukotić, S Kapor, T Dragojević, D Đikić… - … & Molecular Medicine, 2022 - nature.com
Although bone marrow-derived mesenchymal stromal cells (BM-MSCs) have been identified
as a major cellular source of fibrosis, the exact molecular mechanism and signaling …
as a major cellular source of fibrosis, the exact molecular mechanism and signaling …
Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms
The introduction of next-generation sequencing has broadened the genetic landscape of
myeloproliferative neoplasms (MPNs) beyond JAK2, MPL, and CALR. However, the …
myeloproliferative neoplasms (MPNs) beyond JAK2, MPL, and CALR. However, the …
Gene expression profiling distinguishes prefibrotic from overtly fibrotic myeloproliferative neoplasms and identifies disease subsets with distinct inflammatory …
The Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) share similar
molecular characteristics in that they frequently harbor hotspot mutations in JAK2, CALR or …
molecular characteristics in that they frequently harbor hotspot mutations in JAK2, CALR or …
The temporal sequence and the differences in somatic mutation acquisition determines clinical behaviors of JAK2-positive myeloproliferative neoplasms
Background/Aim: We have yet to understand why JAK2-positive myeloproliferative
neoplasms (MPN) patients manifest different phenotypes despite harboring JAK2 mutations …
neoplasms (MPN) patients manifest different phenotypes despite harboring JAK2 mutations …
The Imperative of Implementing Precision Medicine in the Context of Diabetes and Treatment
Precision medicine is a medical approach that involves customizing therapy for an individual
by using extensive biological and external data. The rapid progress in the disciplines of …
by using extensive biological and external data. The rapid progress in the disciplines of …
Philadelphia-negative myeloproliferative neoplasms: laboratory workup in the era of next-generation sequencing
Abstract Purpose of Review To review the impact of next-generation sequencing (NGS) on
laboratory approach of myeloproliferative neoplasms (MPNs). Recent Findings Next …
laboratory approach of myeloproliferative neoplasms (MPNs). Recent Findings Next …
Designing and Simulating the Structure of an Effective Immunotoxin in Breast Cancer
M Maleknejadyazdi… - Personalized Medicine …, 2023 - pmjournal.ir
Immunotoxins have been used for cancer treatment. The immunotoxin binds to the surface
antigen on the cancer cell, enters inside the cell by endocytosis1, and destroys the cancer …
antigen on the cancer cell, enters inside the cell by endocytosis1, and destroys the cancer …
[HTML][HTML] Calreticulin gene mutation in BCR-ABL1 negative myeloproliferative neoplasms: relation to clinical, laboratory and morphological findings
Background Essential thrombocytosis is an indolent myeloproliferative neoplasm (MPN) that
may be complicated by vascular events. This disorder may also transform into more …
may be complicated by vascular events. This disorder may also transform into more …