PEGylation defines the modification of a protein, peptide or non-peptide molecule by the
linking of one or more polyethylene glycol (PEG) chains. This polymer is non-toxic, non …

Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

A large number of methods have been developed over the years to study protein–protein
interactions. Many of these techniques are now available to the nonspecialist researcher …

A wide spectrum of metabolites (mainly, the three major nutrients and their derivatives) can
be sensed by specific sensors, then trigger a series of signal transduction pathways and …

Autophagy is an important biological process that is essential for the removal of damaged
organelles and toxic or aggregated proteins by delivering them to the lysosome for …

Bacterial lipoproteins are a set of membrane proteins with many different functions. Due to
this broad-ranging functionality, these proteins have a considerable significance in many …

The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes.
Its oncogenic counterpart, the Bcr–Abl fusion protein, causes certain human leukaemias …

▪ Abstract Protein S-palmitoylation is the thioester linkage of long-chain fatty acids to
cysteine residues in proteins. Addition of palmitate to proteins facilitates their membrane …

Protein lipid modification involves the attachment of hydrophobic groups to proteins via
ester, thioester, amide, or thioether linkages. In this review, the specific click chemical …

A wide variety of signaling proteins are modified by covalently linked fatty acids and/or
prenyl groups. These hydrophobic moieties, which include myristate, palmitate, farnesyl and …