In the era of individualized medicine, gaps in knowledge remain about sex-specific risk
factors, diagnostic and treatment options that might reduce mortality from cardiovascular …

Reports have correlated the use of estrogen for the treatment of menopausal symptoms with
beneficial effects on the cardiovascular system. Molecular, biochemical, preclinical, and …

The sex steroid hormone estrogen plays a number of regulatory roles in female
development. During menopause, estrogen synthesis in the ovaries decreases, which …

Background Use of menopausal hormonal therapy (MHT)-containing estrogen and a
synthetic progestin is associated with an increased risk of breast cancer. It is unclear if …

Oxidative stress has been implicated in a number of neurodegenerative diseases spanning
various fields of research. Reactive oxygen species can be beneficial or harmful, depending …

Women show a lower incidence of cardiovascular diseases than age‐matched men, but this
benefit disappears after menopause. Oestrogen‐mediated vascular actions are mainly …

Background Menopause poses significant health risks for women, particularly an increased
vulnerability to fractures associated with osteoporosis. Dietary interventions have emerged …

Seventy-five glorious years have passed since estradiol was discovered by Edward Doisy.
From discovery in the ovaries to delineation of diverse physiological effects, research on …

Conjugated estrogens (CE) and Bazedoxifene (BZA) combination is used to alleviate
menopause-associated symptoms in women. CE+ BZA undergo first-pass-metabolism in the …

Loss of ovarian hormones leads to increased adiposity and insulin resistance (IR),
increasing the risk for cardiovascular and metabolic diseases. The purpose of this study was …