With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Traumatic brain injury (TBI), defined as an alteration in brain functions caused by an external
force, is responsible for high morbidity and mortality around the world. It is important to …

Background Traumatic brain injury (TBI) is a complex disorder that is traditionally stratified
based on clinical signs and symptoms. Recent imaging and molecular biomarker …

Since the first pioneering studies in the 1990s, a large number of experimental animal
studies have demonstrated the neuroprotective efficacy of progesterone for brain disorders …

Concussion after a force to the head is called mild traumatic brain injury (mTBI).
Approximately 1 in 5 patients with mTBI will develop chronic pain (headache and …

Traumatic brain injury (TBI) is the cause for long-term disability in more than 3 million
patients in the US alone, with chronic pain being the most frequently reported complain. To …

Intracerebral hemorrhage‐(ICH‐) induced secondary brain injury (SBI) is a very complex
pathophysiological process. However, the molecular mechanisms and drug targets of SBI …

Toxic liver injury causes necrosis and fibrosis, which may lead to cirrhosis and liver failure.
Despite recent progress in understanding the mechanism of liver fibrosis, our knowledge of …

There is an unmet clinical need for objective biomarkers to monitor disease progression and
treatment response in Huntington's disease (HD). The aim of this review is, therefore, to …

Traumatic brain injury is a multifaceted condition that encompasses a spectrum of injuries:
contusions, axonal injuries in specific brain regions, edema, and hemorrhage. Brain injury …