Cell adhesion in cancer: Beyond the migration of single cells

M Janiszewska, MC Primi, T Izard - Journal of biological chemistry, 2020 - ASBMB
Homeostasis in healthy tissues strongly relies on cell-to-cell adhesion and cell-to-
extracellular matrix interactions. For instance, normal epithelial cells maintain tissue …

Virus–receptor interactions: the key to cellular invasion

MS Maginnis - Journal of molecular biology, 2018 - Elsevier
Virus–receptor interactions play a key regulatory role in viral host range, tissue tropism, and
viral pathogenesis. Viruses utilize elegant strategies to attach to one or multiple receptors …

Strategies to address chimeric antigen receptor tonic signaling

A A**a, J Maher - Molecular cancer therapeutics, 2018 - AACR
Adoptive cell transfer using chimeric antigen receptors (CAR) has emerged as one of the
most promising new therapeutic modalities for patients with relapsed or refractory B-cell …

Targeting glioblastoma stem cells: a review on biomarkers, signal pathways and targeted therapy

X Tang, C Zuo, P Fang, G Liu, Y Qiu, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Glioblastoma (GBM) remains the most lethal and common primary brain tumor, even after
treatment with multiple therapies, such as surgical resection, chemotherapy, and radiation …

Glioblastoma cancer stem cell biology: Potential theranostic targets

F Sharifzad, S Ghavami, J Verdi, S Mardpour… - Drug Resistance …, 2019 - Elsevier
Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

N-cadherin upregulation mediates adaptive radioresistance in glioblastoma

S Osuka, D Zhu, Z Zhang, C Li… - The Journal of …, 2021 - Am Soc Clin Investig
Glioblastoma (GBM) is composed of heterogeneous tumor cell populations, including those
with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation …

Cancer-associated angiogenesis: the endothelial cell as a checkpoint for immunological patrolling

AG Solimando, SD Summa, A Vacca, D Ribatti - Cancers, 2020 - mdpi.com
Simple Summary A clinical decision and study design investigating the level and extent of
angiogenesis modulation aimed at vascular normalization without rendering tissues hypoxic …

[HTML][HTML] uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

MA Pavón, I Arroyo-Solera, MV Céspedes… - Oncotarget, 2016 - ncbi.nlm.nih.gov
There is strong evidence supporting the role of the plasminogen activator system in head
and neck squamous cell carcinoma (HNSCC), particularly of its uPA (urokinase …

Transformation of SH-SY5Y cell line into neuron-like cells: Investigation of electrophysiological and biomechanical changes

M Şahin, G Öncü, MA Yılmaz, D Özkan, H Saybaşılı - Neuroscience Letters, 2021 - Elsevier
Abstract SH-SY5Y human neuroblastoma cells are commonly used as neuronal models.
Here, we examined different aspects of SH-SY5Y cell differentiation. Various differentiation …

NADPH oxidases: insights into selected functions and mechanisms of action in cancer and stem cells

M Skonieczna, T Hejmo… - Oxidative Medicine …, 2017 - Wiley Online Library
NADPH oxidases (NOX) are reactive oxygen species‐(ROS‐) generating enzymes
regulating numerous redox‐dependent signaling pathways. NOX are important regulators of …