Coupling mechanism and significance of the BOLD signal: a status report

EMC Hillman - Annual review of neuroscience, 2014 - annualreviews.org
Functional magnetic resonance imaging (fMRI) provides a unique view of the working
human mind. The blood-oxygen-level-dependent (BOLD) signal, detected in fMRI, reflects …

Glial and neuronal control of brain blood flow

D Attwell, AM Buchan, S Charpak, M Lauritzen… - Nature, 2010 - nature.com
Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these
cells control blood flow is crucial for understanding how neural computation is powered, for …

Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy

X Zhu, Q Huang, A DiSpirito, T Vu, Q Rong… - Light: Science & …, 2022 - nature.com
High-speed high-resolution imaging of the whole-brain hemodynamics is critically important
to facilitating neurovascular research. High imaging speed and image quality are crucial to …

Resting-state hemodynamics are spatiotemporally coupled to synchronized and symmetric neural activity in excitatory neurons

Y Ma, MA Shaik, MG Kozberg, SH Kim… - Proceedings of the …, 2016 - pnas.org
Brain hemodynamics serve as a proxy for neural activity in a range of noninvasive
neuroimaging techniques including functional magnetic resonance imaging (fMRI). In …

Wide-field optical map** of neural activity and brain haemodynamics: considerations and novel approaches

Y Ma, MA Shaik, SH Kim… - … of the Royal …, 2016 - royalsocietypublishing.org
Although modern techniques such as two-photon microscopy can now provide cellular-level
three-dimensional imaging of the intact living brain, the speed and fields of view of these …

Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease

J Kur, EA Newman, T Chan-Ling - Progress in retinal and eye research, 2012 - Elsevier
We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

The physics of functional magnetic resonance imaging (fMRI)

RB Buxton - Reports on Progress in Physics, 2013 - iopscience.iop.org
Functional magnetic resonance imaging (fMRI) is a methodology for detecting dynamic
patterns of activity in the working human brain. Although the initial discoveries that led to …

Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease

NB Hamilton, D Attwell, CN Hall - Frontiers in neuroenergetics, 2010 - frontiersin.org
Because regional blood flow increases in association with the increased metabolic demand
generated by localised increases in neural activity, functional imaging researchers often …

Imaging faster neural dynamics with fast fMRI: A need for updated models of the hemodynamic response

JR Polimeni, LD Lewis - Progress in neurobiology, 2021 - Elsevier
Fast fMRI enables the detection of neural dynamics over timescales of hundreds of
milliseconds, suggesting it may provide a new avenue for studying subsecond neural …

High-speed label-free functional photoacoustic microscopy of mouse brain in action

J Yao, L Wang, JM Yang, KI Maslov, TTW Wong, L Li… - Nature …, 2015 - nature.com
We present fast functional photoacoustic microscopy (PAM) for three-dimensional high-
resolution, high-speed imaging of the mouse brain, complementary to other imaging …