HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid …

A Zhitkevich, E Bayurova, D Avdoshina, N Zakirova… - Viruses, 2024 - mdpi.com
The high incidence of epithelial malignancies in HIV-1 infected individuals is associated with
co-infection with oncogenic viruses, such as high-risk human papillomaviruses (HR HPVs) …

Enzymatic activity of HIV-1 protease defines migration of tumor cells in vitro and enhances their metastatic activity in vivo

M Isaguliants, A Zhitkevich, S Petkov, T Gorodnicheva… - Biochimie, 2025 - Elsevier
Overexpression of aspartic proteases, as cathepsin D, is an independent marker of poor
prognosis in breast cancer, correlated with the incidence of clinical metastasis. We aimed to …

Expressed in HPV 16 Infected Epidermoid Carcinoma Cells, HIV‐1 Reverse Transcriptase Shifts Their Metabolism towards aerobic Glycolysis, Induces Hybrid E/M …

AS Zhitkevich, EO Bayurova, DV Avdoshina… - 2023 - preprints.org
High incidence of epithelial malignancies in HIV-1 infection is associated with co-infection
with oncogenic viruses, such as high-risk human papillomaviruses (HR HPVs), most often …