The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023‏ - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

Worldwide emergence of fluconazole-resistant Candida parapsilosis: current framework and future research roadmap

F Daneshnia, JN de Almeida Júnior, M Ilkit… - The Lancet …, 2023‏ - thelancet.com
Candida parapsilosis is one of the most commen causes of life-threatening candidaemia,
particularly in premature neonates, individuals with cancer of the haematopoietic system …

Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants

J Branco, IM Miranda, AG Rodrigues - Journal of Fungi, 2023‏ - mdpi.com
Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …

[HTML][HTML] COVID-19-associated candidiasis (CAC): an underestimated complication in the absence of immunological predispositions?

A Arastehfar, A Carvalho, MH Nguyen, MT Hedayati… - Journal of fungi, 2020‏ - mdpi.com
The recent global pandemic of COVID-19 has predisposed a relatively high number of
patients to acute respiratory distress syndrome (ARDS), which carries a risk of develo** …

The antifungal pipeline: fosmanogepix, ibrexafungerp, olorofim, opelconazole, and rezafungin

M Hoenigl, R Sprute, M Egger, A Arastehfar… - Drugs, 2021‏ - Springer
The epidemiology of invasive fungal infections is changing, with new populations at risk and
the emergence of resistance caused by the selective pressure from increased usage of …

Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020‏ - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

[HTML][HTML] The quiet and underappreciated rise of drug-resistant invasive fungal pathogens

A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020‏ - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …

Resistance to antifungal drugs

R Ben-Ami, DP Kontoyiannis - Infectious Disease Clinics, 2021‏ - id.theclinics.com
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Antifungal drug resistance: an update

DW Denning - European Journal of Hospital Pharmacy, 2022‏ - ejhp.bmj.com
The number of antifungal classes is small, and resistance is becoming a much more
frequent problem. Much greater emphasis needs to be placed on susceptibility testing and …