Atopic dermatitis: pathophysiology
The pathophysiology of atopic dermatitis is complex and multifactorial, involving elements of
barrier dysfunction, alterations in cell mediated immune responses, IgE mediated …
barrier dysfunction, alterations in cell mediated immune responses, IgE mediated …
Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents
T Luger, M Amagai, B Dreno, MA Dagnelie… - Journal of …, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by eczematous
and pruritic skin lesions. In recent decades, the prevalence of AD has increased worldwide …
and pruritic skin lesions. In recent decades, the prevalence of AD has increased worldwide …
Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor
The epidermis forms a barrier that defends the body from desiccation and entry of harmful
substances, while also sensing and integrating environmental signals. The tightly …
substances, while also sensing and integrating environmental signals. The tightly …
Nanostructured lipid carriers: Promising drug delivery systems for future clinics
During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …
Atopic dermatitis in diverse racial and ethnic groups—variations in epidemiology, genetics, clinical presentation and treatment
BP Kaufman, E Guttman‐Yassky… - Experimental …, 2018 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin condition that affects diverse ethnic
groups with varying prevalence. Despite a predominance of studies in individuals of …
groups with varying prevalence. Despite a predominance of studies in individuals of …
The IL-4, IL-13 and IL-31 pathways in atopic dermatitis
C Dubin, E Del Duca… - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is the most common inflammatory skin disease. It has a
complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier …
complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier …
Environmental risk factors and their role in the management of atopic dermatitis
R Kantor, JI Silverberg - Expert review of clinical immunology, 2017 - Taylor & Francis
Introduction: The etiology of atopic dermatitis (AD) is multifactorial with interaction between
genetics, immune and environmental factors. Areas covered: We review the role of prenatal …
genetics, immune and environmental factors. Areas covered: We review the role of prenatal …
The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming
Skin barrier structure and function is essential to human health. Hitherto unrecognized
functions of epidermal keratinocytes show that the skin plays an important role in adapting …
functions of epidermal keratinocytes show that the skin plays an important role in adapting …
Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare
Whole metagenome analysis has the potential to reveal functional triggers of skin diseases,
but issues of cost, robustness and sampling efficacy have limited its application. Here, we …
but issues of cost, robustness and sampling efficacy have limited its application. Here, we …
Atopic dermatitis: a disease of altered skin barrier and immune dysregulation
M Boguniewicz, DYM Leung - Immunological reviews, 2011 - Wiley Online Library
Atopic dermatitis (AD) is an important chronic or relapsing inflammatory skin disease that
often precedes asthma and allergic disorders. New insights into the genetics and …
often precedes asthma and allergic disorders. New insights into the genetics and …