Genetic and epigenetic alterations in Barrett's esophagus and esophageal adenocarcinoma

AM Kaz, WM Grady, MD Stachler… - … Clinics of North …, 2015 - pmc.ncbi.nlm.nih.gov
Esophageal adenocarcinoma (EAC) develops from Barrett's esophagus (BE), a condition
where the normal squamous epithelia is replaced by specialized intestinal metaplasia in …

Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction

K Sugano, SJ Spechler, EM El-Omar, KEL McColl… - Gut, 2022 - gut.bmj.com
Objective An international meeting was organised to develop consensus on (1) the
landmarks to define the gastro-oesophageal junction (GOJ),(2) the occurrence and …

A systematic review of esophageal microRNA markers for diagnosis and monitoring of Barrett's esophagus

R Mallick, SK Patnaik, S Wani, A Bansal - Digestive Diseases and …, 2016 - Springer
Background Esophageal epithelial microRNAs may be used to diagnose Barrett's
esophagus (BE) and possibly monitor its progression to esophageal adenocarcinoma …

Plasmonic nanobiosensors for detection of microRNA cancer biomarkers in clinical samples

BM Crawford, HN Wang, C Stolarchuk… - Analyst, 2020 - pubs.rsc.org
MicroRNAs (miRNAs) play an important role in the regulation of biological processes and
have demonstrated great potential as biomarkers for the early detection of various diseases …

Surface-Enhanced Raman Spectroscopy-Based Detection of Micro-RNA Biomarkers for Biomedical Diagnosis Using a Comparative Study of Interpretable Machine …

JQ Li, H Neng-Wang, AJ Canning… - Applied …, 2024 - journals.sagepub.com
Surface-enhanced Raman spectroscopy (SERS) has wide diagnostic applications due to
narrow spectral features that allow multiplex analysis. We have previously developed a …

Evaluation of miRNA-196a2 and apoptosis-related target genes: ANXA1, DFFA and PDCD4 expression in gastrointestinal cancer patients: A pilot study

MS Fawzy, EA Toraih, A Ibrahiem, H Abdeldayem… - PloS one, 2017 - journals.plos.org
Previous reports have suggested the significant association of miRNAs aberrant expression
with tumor initiation, progression and metastasis in cancer, including gastrointestinal (GI) …

Differential microRNA signatures in the pathogenesis of Barrett's esophagus

MP Craig, S Rajakaruna, O Paliy, M Sajjad… - Clinical and …, 2020 - journals.lww.com
OBJECTIVES: Barrett's esophagus (BE) is the precursor lesion and a major risk factor for
esophageal adenocarcinoma (EAC). Although patients with BE undergo routine endoscopic …

MicroRNA profiles of Barrett's esophagus and esophageal adenocarcinoma: Differences in glandular non-native epithelium

J Drahos, K Schwameis, LD Orzolek… - Cancer Epidemiology …, 2016 - aacrjournals.org
Background: The tissue specificity and robustness of miRNAs may aid risk prediction in
individuals diagnosed with Barrett's esophagus. As an initial step, we assessed whether …

Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma

O Slaby, J Srovnal, L Radova, J Gregar… - …, 2015 - academic.oup.com
Esophageal adenocarcinoma (EAC) is highly aggressive malignancy that frequently
develops from Barrett's esophagus (BE), a premalignant pathologic change occurring in the …

Circulating exosomal miRNAs as potential biomarkers for Barrett's esophagus and esophageal adenocarcinoma

J Lv, HP Zhao, K Dai, Y Cheng… - World Journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Exosomes, a class of extracellular vesicles, are small membrane-bound vesicles derived
from almost all cell types that can play important roles in intercellular communication …