The developments in positron emission tomography (PET) are reviewed with an emphasis
on instrumentation for clinical PET imaging. After a brief summary of positron imaging before …

This review describes the properties of available and emerging radiation detector and read-
out technologies and discusses how they may affect PET scanner performance. After a …

Significant improvements have made it possible to add the technology of time-of-flight (TOF)
to improve PET, particularly for oncology applications. The goals of this work were to …

The ECAT high resolution research tomograph (HRRT) is a dedicated brain and small
animal PET scanner, with design features that enable high image spatial resolution …

Ordered subset expectation maximization (OSEM) is the most widely used algorithm for
clinical PET image reconstruction. OSEM is usually stopped early and post-filtered to control …

Accurate system modeling in tomographic image reconstruction has been shown to reduce
the spatial variance of resolution and improve quantitative accuracy. System modeling can …

SINCE THE INCEPTION of positron emission tomography (PET) several decades ago, PET
scanner design and performance have improved dramatically. The number of detector …

Purpose Image reconstruction including the modelling of the point spread function (PSF) is
an approach improving the resolution of the PET images. This study assessed the …

The microPET Focus 120 scanner is a third-generation animal PET scanner dedicated to
rodent imaging. Here, we report the results of scanner performance testing. Methods: A …

A newly developed simulation toolkit, GATE (Geant4 Application for Tomographic Emission),
was used to develop a Monte Carlo simulation of a fully three-dimensional (3D) clinical PET …