Chronic complications of diabetes are due to myriad disorders of numerous metabolic
pathways that are responsible for most of the morbidity and mortality associated with the …

Diabetic kidney disease (DKD), defined as co-existing diabetes and chronic kidney disease
in the absence of other clear causes of kidney injury, occurs in approximately 20–40% of …

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney
disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic …

Several chemicals, including environmental toxicants and clinically useful drugs, cause
severe cellular damage to different organs of our body through metabolic activation to highly …

Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Renal fibrosis is the histological manifestation of a progressive, usually irreversible process
causing chronic and end-stage kidney disease. We performed genome-wide transcriptome …

The gastrointestinal tract—the largest endocrine network in human physiology—
orchestrates signals from the external environment to maintain neural and hormonal control …

Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide and the
single strongest predictor of mortality in patients with diabetes. DKD is a prototypical disease …

The pathogenesis of diabetic kidney disease (DKD) involves multifactorial processes that
converge to initiate and advance the disease. Although DKD is not typically classified as an …

Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous,
and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate …