Dendritic cell regulation of TH1-TH2 development
M Moser, KM Murphy - Nature immunology, 2000 - nature.com
Understanding the control exerted by cytokines on T helper cell subsets 1 and 2 (TH 1-TH 2)
development has progressed to a fairly satisfying knowledge of intracellular signals and …
development has progressed to a fairly satisfying knowledge of intracellular signals and …
[HTML][HTML] The role of IL-10 in immune regulation during M. tuberculosis infection
PS Redford, PJ Murray, A O'garra - Mucosal immunology, 2011 - Elsevier
During gaseous exchange the lungs are exposed to a vast variety of pathogens, allergens,
and innocuous particles. A feature of the lung immune response to lung-tropic aerosol …
and innocuous particles. A feature of the lung immune response to lung-tropic aerosol …
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
Using a model of lethal oral infection with Toxoplasma gondii, we examined the fate of both
induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses …
induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses …
DC-based cancer vaccines
E Gilboa - The Journal of clinical investigation, 2007 - Am Soc Clin Investig
Because of the large preexisting antigenic load and immunosuppressive environment within
a tumor, inducing therapeutically useful antitumor immunity in cancer patients requires the …
a tumor, inducing therapeutically useful antitumor immunity in cancer patients requires the …
Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8− dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells
Mouse spleen contains three distinct mature dendritic cell (DC) populations (CD4+ 8−,
CD4− 8−, and CD4− 8+) which retain a capacity to take up particulate and soluble Ags …
CD4− 8−, and CD4− 8+) which retain a capacity to take up particulate and soluble Ags …
Generation of human CD8 T regulatory cells by CD40 ligand–activated plasmacytoid dendritic cells
Although CD8 T cell–mediated immunosuppression has been a well-known phenomenon
during the last three decades, the nature of primary CD8 T suppressor cells and the …
during the last three decades, the nature of primary CD8 T suppressor cells and the …
Dendritic cell lineage, plasticity and cross-regulation
Dendritic cells (DCs) are professional antigen-presenting cells that have an extraordinary
capacity to stimulate naïve T cells and initiate primary immune responses. Here we review …
capacity to stimulate naïve T cells and initiate primary immune responses. Here we review …
PI3K-mediated negative feedback regulation of IL-12 production in DCs
T Fukao, M Tanabe, Y Terauchi, T Ota, S Matsuda… - Nature …, 2002 - nature.com
Abstract Although interleukin 12 (IL-12) production by dendritic cells (DCs) confers
protection against harmful invasions by regulating both innate and adaptive immunity, its …
protection against harmful invasions by regulating both innate and adaptive immunity, its …
CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal
CD40 ligation triggers IL-12 production by dendritic cells (DC) in vitro. Here, we demonstrate
that CD40 cross-linking alone is not sufficient to induce IL-12 production by DC in vivo …
that CD40 cross-linking alone is not sufficient to induce IL-12 production by DC in vivo …
Differential production of IL-12, IFN-α, and IFN-γ by mouse dendritic cell subsets
Dendritic cells (DC) not only stimulate T cells effectively but are also producers of cytokines
that have important immune regulatory functions. In this study we have extended information …
that have important immune regulatory functions. In this study we have extended information …