“Bet hedging” against climate change in develo** and adult animals: roles for stochastic gene expression, phenotypic plasticity, epigenetic inheritance and …
Animals from embryos to adults experiencing stress from climate change have numerous
mechanisms available for enhancing their long-term survival. In this review we consider …
mechanisms available for enhancing their long-term survival. In this review we consider …
Disentangling variational bias: the roles of development, mutation, and selection
The extraordinary diversity and adaptive fit of organisms to their environment depends
fundamentally on the availability of variation. While most population genetic frameworks …
fundamentally on the availability of variation. While most population genetic frameworks …
Does strain-level persistence of lactobacilli in long-term back-slopped sourdoughs inform on domestication of food-fermenting lactic acid bacteria?
Sourdoughs are maintained by back-slop** over long time periods. To determine strain-
level persistence of bacteria, we characterized four sourdoughs from bakeries over a period …
level persistence of bacteria, we characterized four sourdoughs from bakeries over a period …
The highly rugged yet navigable regulatory landscape of the bacterial transcription factor TetR
Transcription factor binding sites (TFBSs) are important sources of evolutionary innovations.
Understanding how evolution navigates the sequence space of such sites can be achieved …
Understanding how evolution navigates the sequence space of such sites can be achieved …
Niches for neglected ideas?
D Houle - 2024 - academic.oup.com
Over the last 25 years, a small but persistent group of biologists have argued that
evolutionary biology is overly focused on genetic inheritance and processes that change …
evolutionary biology is overly focused on genetic inheritance and processes that change …
Mutation and selection induce correlations between selection coefficients and mutation rates
The joint distribution of selection coefficients and mutation rates is a key determinant of the
genetic architecture of molecular adaptation. Three different distributions are of immediate …
genetic architecture of molecular adaptation. Three different distributions are of immediate …
AadT, a new weapon in Acinetobacter's fight against antibiotics
Genes encoding a novel multidrug efflux pump, AadT, from the Drug: H+ antiporter 2 family,
were discovered in Acinetobacter multidrug resistance plasmids. Here, we profiled the …
were discovered in Acinetobacter multidrug resistance plasmids. Here, we profiled the …
Bias in the arrival of variation can dominate over natural selection in Richard Dawkins's biomorphs
Biomorphs, Richard Dawkins's iconic model of morphological evolution, are traditionally
used to demonstrate the power of natural selection to generate biological order from random …
used to demonstrate the power of natural selection to generate biological order from random …
Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
S Hsiao, S Chen, Y Jiang, Q Wang, Y Yang… - Advanced …, 2024 - Wiley Online Library
The current‐generation adenine base editor (ABE) ABE8e, which has evolved from the
prokaryotic evolution system, exhibits high efficiency in mediating A‐to‐G conversion and is …
prokaryotic evolution system, exhibits high efficiency in mediating A‐to‐G conversion and is …
Distribution of mutation rates challenges evolutionary predictability
TA Sun, PA Lind - Microbiology, 2023 - microbiologyresearch.org
Natural selection is commonly assumed to act on extensive standing genetic variation. Yet,
accumulating evidence highlights the role of mutational processes creating this genetic …
accumulating evidence highlights the role of mutational processes creating this genetic …