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Local and systemic mechanisms that control the hair follicle stem cell niche
Hair follicles are essential appendages of the mammalian skin, as hair performs vital
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …
The sympathetic nervous system in development and disease
E Scott-Solomon, E Boehm, R Kuruvilla - Nature Reviews …, 2021 - nature.com
The sympathetic nervous system prepares the body for 'fight or flight'responses and
maintains homeostasis during daily activities such as exercise, eating a meal or regulation …
maintains homeostasis during daily activities such as exercise, eating a meal or regulation …
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …
[HTML][HTML] Molecular architecture of the mouse nervous system
The mammalian nervous system executes complex behaviors controlled by specialized,
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …
precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a …
[HTML][HTML] Somatotopic organization and intensity dependence in driving distinct NPY-expressing sympathetic pathways by electroacupuncture
S Liu, ZF Wang, YS Su, RS Ray, XH **g, YQ Wang… - Neuron, 2020 - cell.com
The neuroanatomical basis behind acupuncture practice is still poorly understood. Here, we
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …
Genetic map** of cell type specificity for complex traits
K Watanabe, M Umićević Mirkov, CA de Leeuw… - Nature …, 2019 - nature.com
Single-cell RNA sequencing (scRNA-seq) data allows to create cell type specific
transcriptome profiles. Such profiles can be aligned with genome-wide association studies …
transcriptome profiles. Such profiles can be aligned with genome-wide association studies …
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease
KA Ziegler, A Ahles, A Dueck, D Esfandyari, P Pichler… - Science, 2023 - science.org
Disruption of the physiologic sleep-wake cycle and low melatonin levels frequently
accompany cardiac disease, yet the underlying mechanism has remained enigmatic …
accompany cardiac disease, yet the underlying mechanism has remained enigmatic …
γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis
The sympathetic nervous system innervates peripheral organs to regulate their function and
maintain homeostasis, whereas target cells also produce neurotrophic factors to promote …
maintain homeostasis, whereas target cells also produce neurotrophic factors to promote …
Targeting peripheral somatosensory neurons to improve tactile-related phenotypes in ASD models
Somatosensory over-reactivity is common among patients with autism spectrum disorders
(ASDs) and is hypothesized to contribute to core ASD behaviors. However, effective …
(ASDs) and is hypothesized to contribute to core ASD behaviors. However, effective …
[HTML][HTML] Sympathetic neuropeptide Y protects from obesity by sustaining thermogenic fat
Human mutations in neuropeptide Y (NPY) have been linked to high body mass index but
not altered dietary patterns. Here we uncover the mechanism by which NPY in sympathetic …
not altered dietary patterns. Here we uncover the mechanism by which NPY in sympathetic …