Neuroimaging and fluid biomarkers in Parkinson's disease in an era of targeted interventions

A Zarkali, GEC Thomas, H Zetterberg… - Nature …, 2024 - nature.com
A major challenge in Parkinson's disease is the variability in symptoms and rates of
progression, underpinned by heterogeneity of pathological processes. Biomarkers are …

[HTML][HTML] NODDI in clinical research

K Kamiya, M Hori, S Aoki - Journal of neuroscience methods, 2020 - Elsevier
Diffusion MRI (dMRI) has proven to be a useful imaging approach for both clinical diagnosis
and research investigating the microstructures of nervous tissues, and it has helped us to …

Cerebral microstructural alterations in Post-COVID-condition are related to cognitive impairment, olfactory dysfunction and fatigue

JA Hosp, M Reisert, A Dressing, V Götz… - Nature …, 2024 - nature.com
After contracting COVID-19, a substantial number of individuals develop a Post-COVID-
Condition, marked by neurologic symptoms such as cognitive deficits, olfactory dysfunction …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

The evolution of white matter microstructural changes after mild traumatic brain injury: a longitudinal DTI and NODDI study

EM Palacios, JP Owen, EL Yuh, MB Wang… - Science …, 2020 - science.org
Neuroimaging biomarkers that can detect white matter (WM) pathology after mild traumatic
brain injury (mTBI) and predict long-term outcome are needed to improve care and develop …

MR biomarkers of degenerative brain disorders derived from diffusion imaging

C Andica, K Kamagata, T Hatano… - Journal of Magnetic …, 2020 - Wiley Online Library
The incidence of neurodegenerative diseases has shown an increasing trend. These
conditions typically cause progressive functional disability. Identification of robust …

[HTML][HTML] Diffusion magnetic resonance imaging-based biomarkers for neurodegenerative diseases

K Kamagata, C Andica, A Kato, Y Saito… - International Journal of …, 2021 - mdpi.com
There has been an increasing prevalence of neurodegenerative diseases with the rapid
increase in aging societies worldwide. Biomarkers that can be used to detect pathological …

Neurite orientation dispersion and density imaging (NODDI) and free‐water imaging in Parkinsonism

T Mitchell, DB Archer, WT Chu… - Human Brain …, 2019 - Wiley Online Library
Neurite orientation dispersion and density imaging (NODDI) uses a three‐compartment
model to probe brain tissue microstructure, whereas free‐water (FW) imaging models two …

Cortical microstructure in young onset Alzheimer's disease using neurite orientation dispersion and density imaging

TD Parker, CF Slattery, J Zhang… - Human brain …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is associated with extensive alterations in grey matter
microstructure, but our ability to quantify this in vivo is limited. Neurite orientation dispersion …

Cortical microstructural alterations in mild cognitive impairment and Alzheimer's disease dementia

NM Vogt, JF Hunt, N Adluru, DC Dean III… - Cerebral …, 2020 - academic.oup.com
In Alzheimer's disease (AD), neurodegenerative processes are ongoing for years prior to the
time that cortical atrophy can be reliably detected using conventional neuroimaging …