Myocarditis is an inflammatory disease of the heart that may occur because of infections,
immune system activation, or exposure to drugs. The diagnosis of myocarditis has changed …

Importance Acute myocarditis, defined as a sudden inflammatory injury to the myocardium,
affects approximately 4 to 14 people per 100 000 each year globally and is associated with …

Purpose Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a high-
risk subtype of childhood ALL characterized by kinase-activating alterations that are …

Disease overview The eosinophilias encompass a broad range of non‐hematologic
(secondary or reactive) and hematologic (primary or clonal) disorders with potential for end …

Disease overview The eosinophilias encompass a broad range of nonhematologic
(secondary or reactive) and hematologic (primary, clonal) disorders with potential for end …

Deregulated activity of BCR-ABL1, a nonreceptor tyrosine kinase encoded by the fusion
gene resulting from the t (9; 22)(q34; q11) chromosomal translocation, is thought to be the …

Abstract Disease Overview The eosinophilias encompass a broad range of nonhematologic
(secondary or reactive) and hematologic (primary or clonal) disorders with potential for end …

Myeloid malignancies are clonal disorders that are characterized by acquired somatic
mutation in hematopoietic progenitors. Recent advances in our understanding of the genetic …

PDGFs and their cognate tyrosine kinase α-and β-receptors are involved in multiple tumor-
associated processes including autocrine growth stimulation of tumor cells, stimulation of …

Peripheral T cell lymphoma, unspecified (PTCL/U), the most common form of PTCL, displays
heterogeneous morphology and phenotype, poor response to treatment, and poor …