Antimicrobial peptides are an attractive alternative to traditional antibiotics, due to their
physicochemical properties, activity toward a broad spectrum of bacteria, and mode-of …

Extensive research has been undertaken in the pursuit of anticancer therapeutics. Many
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …

Acquired drug resistance is the major cause for disease recurrence in cancer patients, and
this is particularly true for patients with metastatic melanoma that carry a BRAF V600E …

Cross-linking strategies have found wide applications in chemical biology, enabling the
labeling of biomolecules and monitoring of protein–protein interactions. Nitrone exhibits …

Cyclotides are plant-derived peptides characterized by an∼ 30-amino acid–long cyclic
backbone and a cystine knot motif. Cyclotides have diverse bioactivities, and their …

We evaluated the activity of core‐shell ZnO nanoparticles (ZnO‐NPs@ polymer shell)
containing Oxaliplatin via polymerization through in vitro studies and in vivo mouse models …

Anticancer chemo-and targeted therapies are limited in some cases due to strong side
effects and/or drug resistance. Peptides have received renascent interest as anticancer …

Peptides are being developed as targeted anticancer drugs to modulate cytosolic protein–
protein interactions involved in cancer progression. However, their use as therapeutics is …

Cell penetrating peptides (CPPs) are valuable tools for develo** anticancer therapies due
to their ability to access intracellular targets, including protein–protein interactions. cPF4PD …

Abstract Lactate dehydrogenase 5 (LDH5) is overexpressed in many cancers and is a
potential target for anticancer therapy due to its role in aerobic glycolysis. Small-molecule …