[HTML][HTML] Novel insights into regulators and functional modulators of adipogenesis

HY Kim, HJ Jang, S Muthamil, UC Shin, JH Lyu… - Biomedicine & …, 2024‏ - Elsevier
Adipogenesis is a process that differentiates new adipocytes from precursor cells and is
tightly regulated by several factors, including many transcription factors and various post …

Epigenetic regulation of TGF-β pathway and its role in radiation response

Y Ding, G Zhou, W Hu - International Journal of Radiation Biology, 2024‏ - Taylor & Francis
Purpose Transforming growth factor (TGF-β) plays a dual role in tumor progression as well
as a pivotal role in radiation response. TGF-β-related epigenetic regulations, including DNA …

Development of a TGF-β signaling-related genes signature to predict clinical prognosis and immunotherapy responses in clear cell renal cell carcinoma

X Wu, W **e, B Gong, B Fu, W Chen, L Zhou… - Frontiers in …, 2023‏ - frontiersin.org
Background Transforming growth factor (TGF)-β signaling is strongly related to the
development and progression of tumor. We aimed to construct a prognostic gene signature …

Epigenetic regulation of TGF-β and vice versa in cancers–A review on recent developments

A Naik, N Thakur - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024‏ - Elsevier
This review explores the complex relationship between epigenetic mechanisms and
Transforming Growth Factor-beta (TGF-β) signalling pathways in the field of cancer …

Functioning and mechanisms of PTMs in renal diseases

Z Liu, J Yang, M Du, W **n - Frontiers in Pharmacology, 2023‏ - frontiersin.org
Post-translational modifications (PTMs) are crucial epigenetic mechanisms that regulate
various cellular biological processes. The use of mass spectrometry (MS)-proteomics has …

Kidney cancer: From tumor biology to innovative therapeutics

L Rinaldi, E Senatore, S Feliciello, F Chiuso… - … et Biophysica Acta (BBA …, 2024‏ - Elsevier
Renal cell carcinoma (RCC) constitutes the most frequent kidney cancer of the adult
population and one of the most lethal malignant tumors worldwide. RCC often presents …

[HTML][HTML] Unveiling the metal-dependent aggregation properties of the C-terminal region of amyloidogenic intrinsically disordered protein isoforms DPF3b and DPF3a

T Leyder, J Mignon, D Mottet, C Michaux - International Journal of …, 2022‏ - mdpi.com
Double-PHD fingers 3 (DPF3) is a BAF-associated human epigenetic regulator, which is
increasingly recognised as a major contributor to various pathological contexts, such as …

Crosstalk between metabolic and epigenetic modifications during cell carcinogenesis

Y Gao, X Zhang, Y Du, T Ni, S Hao - Iscience, 2024‏ - cell.com
Genetic mutations arising from various internal and external factors drive cells to become
cancerous. Cancerous cells undergo numerous changes, including metabolic …

The important role of the histone acetyltransferases p300/CBP in cancer and the promising anticancer effects of p300/CBP inhibitors

X Wu, X Zhang, S Tang, Y Wang - Cell Biology and Toxicology, 2025‏ - Springer
Histone acetyltransferases p300 (E1A-associated protein p300) and CBP (CREB binding
protein), collectively known as p300/CBP due to shared sequence and functional synergy …

The clinical utilization of SNIP1 and its pathophysiological mechanisms in disease

Y Chen, W Guo, X Guo, Q Wanqing, Z Yin - Heliyon, 2024‏ - cell.com
Smad intranuclear binding protein 1 (SNIP1), a highly conserved nuclear protein, functions
as a transcriptional regulator and exerts a significant influence on disease progression. In …