Biosynthesis of citrus flavonoids and their health effects
Citrus-derived flavonoids play important roles in the regulation of physiological conditions of
citrus plants, including color changes of flower and fruit, flavor development, and anti-stress …
citrus plants, including color changes of flower and fruit, flavor development, and anti-stress …
Phytochemistry and bioactivity of Citrus flavonoids: a focus on antioxidant, anti-inflammatory, anticancer and cardiovascular protection activities
L Yi, S Ma, D Ren - Phytochemistry Reviews, 2017 - Springer
Epidemiological studies have suggested an inverse relationship between increased
consumption of fruits and reduced risk of chronic diseases, such as cardiovascular diseases …
consumption of fruits and reduced risk of chronic diseases, such as cardiovascular diseases …
Dietary tangeretin alleviated dextran sulfate sodium-induced colitis in mice via inhibiting inflammatory response, restoring intestinal barrier function, and modulating …
In this study, the preventive effect of tangeretin (TAN), a natural flavonoid derivative from
citrus fruits, on the dextran sulfate sodium (DSS)-induced colitis in mice was evaluated. Our …
citrus fruits, on the dextran sulfate sodium (DSS)-induced colitis in mice was evaluated. Our …
Anticancer Activity of Novel Plant Extracts and Compounds from Adenosma bracteosum (Bonati) in Human Lung and Liver Cancer Cells
Cancer is the second leading cause of death globally, and despite the advances in drug
development, it is still necessary to develop new plant-derived medicines. Compared with …
development, it is still necessary to develop new plant-derived medicines. Compared with …
The Multifunctional Effects of Nobiletin and Its Metabolites In Vivo and In Vitro
H Huang, L Li, W Shi, H Liu, J Yang… - Evidence‐Based …, 2016 - Wiley Online Library
Nobiletin (NOB) chemically known as 5, 6, 7, 8, 3′, 4′‐hexamethoxyflavone is a dietary
polymethoxylated flavonoid found in Citrus fruits. Recent evidences show that NOB is a …
polymethoxylated flavonoid found in Citrus fruits. Recent evidences show that NOB is a …
Fast Separation and Sensitive Quantitation of Polymethoxylated Flavonoids in the Peels of Citrus Using UPLC-Q-TOF-MS
TT **ng, XJ Zhao, YD Zhang, YF Li - Journal of Agricultural and …, 2017 - ACS Publications
A rapid, sensitive, and efficient ultraperformance liquid chromatography coupled with
quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) method has been …
quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) method has been …
Nobiletin as a chemopreventive natural product against cancer, a comprehensive review
YY Chen, JJ Liang, DL Wang, JB Chen… - Critical Reviews in …, 2023 - Taylor & Francis
As a leading cause of death, second only to heart disease, cancer has always been one of
the burning topics in medical research. When targeting multiple signal pathways in …
the burning topics in medical research. When targeting multiple signal pathways in …
Nobiletin and its colonic metabolites suppress colitis-associated colon carcinogenesis by down-regulating iNOS, inducing antioxidative enzymes and arresting cell …
Nobiletin (NOB) is a major citrus polymethoxyflavone (PMF) with various beneficial
biological activities. We reported previously that dietary NOB significantly inhibited colitis …
biological activities. We reported previously that dietary NOB significantly inhibited colitis …
In-vivo biotransformation of citrus functional components and their effects on health
Citrus, one of the most popular fruits worldwide, contains various functional components,
including flavonoids, dietary fibers (DFs), essential oils (EOs), synephrines, limonoids, and …
including flavonoids, dietary fibers (DFs), essential oils (EOs), synephrines, limonoids, and …
A metabolite of nobiletin, 4′-demethylnobiletin and atorvastatin synergistically inhibits human colon cancer cell growth by inducing G0/G1 cell cycle arrest and …
Combining different chemopreventive agents is a promising strategy to reduce cancer
incidence and mortality due to potential synergistic interactions between these agents …
incidence and mortality due to potential synergistic interactions between these agents …