Neuroinflammation and depression: microglia activation, extracellular microvesicles and microRNA dysregulation
D Brites, A Fernandes - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Patients with chronic inflammation are often associated with the emergence of depression
symptoms, while diagnosed depressed patients show increased levels of circulating …
symptoms, while diagnosed depressed patients show increased levels of circulating …
Non-exosomal and exosomal circulatory microRNAs: which are more valid as biomarkers?
NNSB Nik Mohamed Kamal… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25
nucleotides that are involved in regulating a range of developmental and physiological …
nucleotides that are involved in regulating a range of developmental and physiological …
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin
MicroRNAs regulate gene expression posttranscriptionally and function within the cells in
which they are transcribed. However, recent evidence suggests that microRNAs can be …
which they are transcribed. However, recent evidence suggests that microRNAs can be …
Combined evaluation of a panel of protein and miRNA serum‐exosome biomarkers for pancreatic cancer diagnosis increases sensitivity and specificity
B Madhavan, S Yue, U Galli, S Rana… - … journal of cancer, 2015 - Wiley Online Library
Late diagnosis contributes to pancreatic cancer (PaCa) dismal prognosis, urging for reliable,
early detection. Serum‐exosome protein and/or miRNA markers might be suitable …
early detection. Serum‐exosome protein and/or miRNA markers might be suitable …
Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer
Introduction Exosomes are 30-100 nm membrane vesicles of endocytic origin, mediating
diverse biological functions including tumor cell invasion, cell-cell communication and …
diverse biological functions including tumor cell invasion, cell-cell communication and …
Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
The impact of hemolysis on cell-free microRNA biomarkers
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …
Biases in small RNA deep sequencing data
CA Raabe, TH Tang, J Brosius… - Nucleic acids …, 2014 - academic.oup.com
High-throughput RNA sequencing (RNA-seq) is considered a powerful tool for novel gene
discovery and fine-tuned transcriptional profiling. The digital nature of RNA-seq is also …
discovery and fine-tuned transcriptional profiling. The digital nature of RNA-seq is also …
Circulating miRNAs as sensitive and specific biomarkers for the diagnosis and monitoring of human diseases: promises and challenges
V De Guire, R Robitaille, N Tetreault, R Guerin… - Clinical …, 2013 - Elsevier
The regulation and modulation of gene expression has been a central focus of modern
biomedical research ever since the first molecular elucidation of DNA. The cellular …
biomedical research ever since the first molecular elucidation of DNA. The cellular …