Immunoglobulin E (IgE)-associated allergy is the most common immune disorder. More than
30% of the population suffer from symptoms of allergy which are often severe, disabling, and …

Ambrosia artemisiifolia, also known as common or short ragweed, is an invasive annual
flowering herbaceous plant that has its origin in North America. Nowadays, ragweed can be …

Immune checkpoint inhibitors have improved clinical outcomes associated with numerous
cancers, but high-grade, immune-related adverse events can occur, particularly with …

Background Prediction of T cell immunogenicity is a topic of considerable interest, both in
terms of basic understanding of the mechanisms of T cells responses and in terms of …

Epitopes, in the context of T cell recognition, are short peptides typically derived by antigen
processing, and presented on the cell surface bound to MHC molecules (HLA molecules in …

Background. Each year dengue virus (DENV) infects 400 million human but causes
symptomatic disease in only a subset of patients, suggesting that host genetic factors may …

In the present review, we summarize work from our as well as other groups related to the
characterization of bacterial T cell epitopes, with a specific focus on two important …

Antigen uptake and processing of exogenous proteins is critical for adaptive immunity,
particularly for T helper cell activation. Proteins undergo distinct proteolytic processing in …

Abstract Background Immunoglobulin (Ig) E-associated allergies result from misguided
immune responses against innocuous antigens. CD4+ T lymphocytes are critical for …

Background Profilins are dominant pan‐allergens known to cause cross‐sensitization,
leading to clinical symptoms such as pollen‐food syndrome. This study aimed to determine …