Polymersome-based protein drug delivery–quo vadis?
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …
approaches and represent one of the fastest growing families of drugs. While many of these …
Advances in block copolymer-phospholipid hybrid vesicles: from physical-chemical properties to applications
Hybrid vesicles, made of lipids and amphiphilic block copolymers, have become
increasingly popular thanks to their versatile properties that enable the construction of …
increasingly popular thanks to their versatile properties that enable the construction of …
Light-triggered nitric oxide (NO) release from photoresponsive polymersomes for corneal wound healing
Polymersomes have been extensively used in the delivery of both small and
macromolecular payloads. However, the controlled delivery of gaseous therapeutics (eg …
macromolecular payloads. However, the controlled delivery of gaseous therapeutics (eg …
Artificial organelles: towards adding or restoring intracellular activity
RAJF Oerlemans, SBPE Timmermans… - …, 2021 - Wiley Online Library
Compartmentalization is one of the main characteristics that define living systems. Creating
a physically separated microenvironment allows nature a better control over biological …
a physically separated microenvironment allows nature a better control over biological …
Advancing biomimetic functions of synthetic cells through compartmentalized cell-free protein synthesis
Synthetic cells are artificial constructs that mimic the structures and functions of living cells.
They are attractive for studying diverse biochemical processes and elucidating the origins of …
They are attractive for studying diverse biochemical processes and elucidating the origins of …
Recent advances in functional nanomaterials for catalytic generation of nitric oxide: a mini review
As a gaseous second messenger, nitric oxide (NO) plays an important role in a series of
signal pathways. Research on the NO regulation for various disease treatments has aroused …
signal pathways. Research on the NO regulation for various disease treatments has aroused …
[HTML][HTML] Membrane composition of polymer-lipid hybrid vesicles
Hybrid vesicles (HVs) assembled from phospholipids and amphiphilic block copolymers
(BCPs) are a more recent alternative to liposomes and polymersomes. We aim to change …
(BCPs) are a more recent alternative to liposomes and polymersomes. We aim to change …
Compartmentalized intracellular click chemistry with biodegradable polymersomes
RAJF Oerlemans, J Shao… - Macromolecular …, 2023 - Wiley Online Library
Polymersome nanoreactors that can be employed as artificial organelles have gained much
interest over the past decades. Such systems often include biological catalysts (ie, enzymes) …
interest over the past decades. Such systems often include biological catalysts (ie, enzymes) …
Cell mimicry as a bottom‐up strategy for hierarchical engineering of nature‐inspired entities
Artificial biology is an emerging concept that aims to design and engineer the structure and
function of natural cells, organelles, or biomolecules with a combination of biological and …
function of natural cells, organelles, or biomolecules with a combination of biological and …
Mucopenetrating polymer–Lipid hybrid nanovesicles as subunits in alginate beads as an oral formulation
E Taipaleenmäki, G Christensen, E Brodszkij… - Journal of Controlled …, 2020 - Elsevier
Crossing the intestinal mucus layer remains a great hurdle in oral drug delivery. The viscous
mucus gel protects the body from pathogens but simultaneously traps many types of delivery …
mucus gel protects the body from pathogens but simultaneously traps many types of delivery …