Abstract The aluminium-[18F] fluoride ([18F] AlF) radiolabelling method combines the
favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal …

Introduction: Despite remarkable advances in tumor treatment, many patients still die from
common tumors (breast, prostate, lung, CNS, colon, and pancreas), and thus, new …

Due to its ideal physical properties, fluorine-18 turns out to be a key radionuclide for positron
emission tomography (PET) imaging, for both preclinical and clinical applications. However …

Gastrin-releasing peptide receptors (GRPRs), part of the bombesin (BBN) family, are
aberrantly overexpressed in many cancers, including those of the breast, prostate, pancreas …

Unorthodox 18F-labeling strategies not employing the formation of a carbon-18F bond are
seldom found in radiochemistry. Historically, the formation of a boron-or silicon-18F bond …

This study aimed to document the first-in-human application of a 68Ga-labeled
heterodimeric peptide BBN-RGD (bombesin-RGD) that targets both integrin αvβ3 and …

Purpose: This study was to assess a gastrin-releasing peptide receptor (GRPR) and integrin
αvβ3 dual targeting tracer 68 Ga-BBN-RGD for positron emission tomography …

Breast cancer is one of the most common malignancies in women, with high morbidity and
mortality rates. In breast cancer, the use of novel radiopharmaceuticals in nuclear medicine …

The incorporation of silicon fluoride acceptor (SiFA) moieties into a variety of molecules,
such as peptides, proteins and biologically relevant small molecules, has improved the …

Imaging plays an important role in prostate cancer (PC), including accurate evaluation of the
extent of disease, assessment of sites of recurrent disease, and monitoring of response to …