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Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer
Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
[HTML][HTML] A review of exosomal isolation methods: is size exclusion chromatography the best option?
K Sidhom, PO Obi, A Saleem - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …
Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small …
Small extracellular vesicles (sEVs) provide major promise for advances in cancer
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
diagnostics, prognostics, and therapeutics, ascribed to their distinctive cargo reflective of …
[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …
various origins. EVs play a crucial role in cellular communication and mediate several …
Challenges in the development and establishment of exosome-based drug delivery systems
J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
[HTML][HTML] A comprehensive review on the composition, biogenesis, purification, and multifunctional role of exosome as delivery vehicles for cancer therapy
J Li, Y Zhang, PY Dong, GM Yang… - Biomedicine & …, 2023 - Elsevier
All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …
[HTML][HTML] Engineering exosome-based biomimetic nanovehicles for wound healing
A Joorabloo, T Liu - Journal of Controlled Release, 2023 - Elsevier
Complexity and difficulties in wound management are pressing concerns that affect patients'
quality of life and may result in tissue infection, necrosis, and loss of local and systemic …
quality of life and may result in tissue infection, necrosis, and loss of local and systemic …
[HTML][HTML] Commonly used methods for extracellular vesicles' enrichment: Implications in downstream analyses and use
M Clos-Sansalvador, M Monguió-Tortajada… - European Journal of …, 2022 - Elsevier
Extracellular vesicles (EVs) are becoming promising tools for clinical application, either as
sources of disease-specific molecular signatures for the unraveling of disease …
sources of disease-specific molecular signatures for the unraveling of disease …
Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina
Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded
with therapeutic molecules and engineered for retention by specific tissues. However …
with therapeutic molecules and engineered for retention by specific tissues. However …
Separation, characterization, and standardization of extracellular vesicles for drug delivery applications
Extracellular vesicles (EVs) are membranous nanovesicles secreted from living cells,
shuttling macromolecules in intercellular communication and potentially possessing intrinsic …
shuttling macromolecules in intercellular communication and potentially possessing intrinsic …