Forensic DNA Phenoty**: Predicting human appearance from crime scene material for investigative purposes

M Kayser - Forensic Science International: Genetics, 2015 - Elsevier
Forensic DNA Phenoty** refers to the prediction of appearance traits of unknown sample
donors, or unknown deceased (missing) persons, directly from biological materials found at …

Improving human forensics through advances in genetics, genomics and molecular biology

M Kayser, P De Knijff - Nature Reviews Genetics, 2011 - nature.com
Forensic DNA profiling currently allows the identification of persons already known to
investigating authorities. Recent advances have produced new types of genetic markers …

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

G Davies, M Lam, SE Harris, JW Trampush… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration

JA Revez, T Lin, Z Qiao, A Xue, Y Holtz, Z Zhu… - Nature …, 2020 - nature.com
Vitamin D deficiency is a candidate risk factor for a range of adverse health outcomes. In a
genome-wide association study of 25 hydroxyvitamin D (25OHD) concentration in 417,580 …

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

RK Walters, R Polimanti, EC Johnson… - Nature …, 2018 - nature.com
Liability to alcohol dependence (AD) is heritable, but little is known about its complex
polygenic architecture or its genetic relationship with other disorders. To discover loci …

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

P Gormley, V Anttila, BS Winsvold, P Palta, T Esko… - Nature …, 2016 - nature.com
Migraine is a debilitating neurological disorder affecting around one in seven people
worldwide, but its molecular mechanisms remain poorly understood. There is some debate …

A direct test of the diathesis–stress model for depression

L Colodro-Conde, B Couvy-Duchesne, G Zhu… - Molecular …, 2018 - nature.com
The diathesis–stress theory for depression states that the effects of stress on the depression
risk are dependent on the diathesis or vulnerability, implying multiplicative interactive effects …

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

J Yang, T Ferreira, AP Morris, SE Medland… - Nature …, 2012 - nature.com
We present an approximate conditional and joint association analysis that can use summary-
level statistics from a meta-analysis of genome-wide association studies (GWAS) and …

Protein-coding repeat polymorphisms strongly shape diverse human phenotypes

RE Mukamel, RE Handsaker, MA Sherman, AR Barton… - Science, 2021 - science.org
Many human proteins contain domains that vary in size or copy number because of variable
numbers of tandem repeats (VNTRs) in protein-coding exons. However, the relationships of …

Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect

L Broer, V Codd, DR Nyholt, J Deelen… - European journal of …, 2013 - nature.com
Telomere length (TL) has been associated with aging and mortality, but individual
differences are also influenced by genetic factors, with previous studies reporting heritability …