The formation of functional neural circuits in the vertebrate central nervous system (CNS)
requires that appropriate numbers of the correct types of neuronal and glial cells are …

The discovery of the sensory nature of the carotid body dates back to the beginning of the
20th century. Following these seminal discoveries, research into carotid body mechanisms …

Thymus is necessary for lifelong immunological tolerance and immunity. It displays a
distinctive epithelial complexity and undergoes age-dependent atrophy. Nonetheless, it also …

The high-grade pulmonary neuroendocrine tumors, small cell lung cancer (SCLC) and large
cell neuroendocrine carcinoma (LCNEC), remain among the most deadly malignancies …

Direct lineage reprogramming is a promising approach for human disease modeling and
regenerative medicine, with poorly understood mechanisms. Here, we reveal a hierarchical …

Cellular differentiation and lineage commitment are considered to be robust and irreversible
processes during development. Recent work has shown that mouse and human fibroblasts …

Direct conversion of nonneural cells to functional neurons holds great promise for
neurological disease modeling and regenerative medicine. We previously reported rapid …

Pathology and Genetics of Head and Neck Tumoursis the latest volume in the new WHO
series, on histological and genetic ty** of human tumours. This authoritative, concise …

The basic helix-loop-helix transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate fate
choice of neurons, astrocytes, and oligodendrocytes, respectively. These same factors are …

The helix-loop-helix (HLH) family of transcriptional regulatory proteins are key players in a
wide array of developmental processes. Over 240 HLH proteins have been identified to date …