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Two-photon calcium imaging of neuronal activity
C Grienberger, A Giovannucci, W Zeiger… - Nature Reviews …, 2022 - nature.com
In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …
activity in the intact brain. It is based on the principle that, when neurons fire action …
Imaging calcium in neurons
C Grienberger, A Konnerth - Neuron, 2012 - cell.com
Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …
Spontaneous cortical activity alternates between motifs defined by regional axonal projections
MH Mohajerani, AW Chan, M Mohsenvand… - Nature …, 2013 - nature.com
Using millisecond-timescale voltage-sensitive dye imaging in lightly anesthetized or awake
adult mice, we show that a palette of sensory-evoked and hemisphere-wide activity motifs …
adult mice, we show that a palette of sensory-evoked and hemisphere-wide activity motifs …
Network-level control of frequency tuning in auditory cortex
HK Kato, SK Asinof, JS Isaacson - Neuron, 2017 - cell.com
Lateral inhibition is a fundamental circuit operation that sharpens the tuning properties of
cortical neurons. This operation is classically attributed to an increase in GABAergic synaptic …
cortical neurons. This operation is classically attributed to an increase in GABAergic synaptic …
Rescue of long-range circuit dysfunction in Alzheimer's disease models
Alzheimer's disease (AD) is associated with defects of synaptic connectivity. Such defects
may not be restricted to local neuronal interactions but may extend to long-range brain …
may not be restricted to local neuronal interactions but may extend to long-range brain …
Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence
K Zhang, R Förster, W He, X Liao, J Li, C Yang… - Nature …, 2021 - nature.com
Memory persistence is a fundamental cognitive process for guiding behaviors and is
considered to rely mostly on neuronal and synaptic plasticity. Whether and how astrocytes …
considered to rely mostly on neuronal and synaptic plasticity. Whether and how astrocytes …
Making waves: initiation and propagation of corticothalamic Ca2+ waves in vivo
Corticothalamic slow oscillations of neuronal activity determine internal brain states. At least
in the cortex, the electrical activity is associated with large neuronal Ca 2+ transients. Here …
in the cortex, the electrical activity is associated with large neuronal Ca 2+ transients. Here …
Mesoscale map** of mouse cortex reveals frequency-dependent cycling between distinct macroscale functional modules
Connectivity map** based on resting-state activity in mice has revealed functional motifs
of correlated activity. However, the rules by which motifs organize into larger functional …
of correlated activity. However, the rules by which motifs organize into larger functional …
Robustness of cortical topography across fields, laminae, anesthetic states, and neurophysiological signal types
W Guo, AR Chambers, KN Darrow… - Journal of …, 2012 - jneurosci.org
Topographically organized maps of the sensory receptor epithelia are regarded as
cornerstones of cortical organization as well as valuable readouts of diverse biological …
cornerstones of cortical organization as well as valuable readouts of diverse biological …
The claustrum supports resilience to distraction
G Atlan, A Terem, N Peretz-Rivlin, K Sehrawat… - Current Biology, 2018 - cell.com
A barrage of information constantly assaults our senses, of which only a fraction is relevant
at any given point in time. However, the neural circuitry supporting the suppression of …
at any given point in time. However, the neural circuitry supporting the suppression of …