Abstract Angiotensin (Ang)‐converting enzyme (ACE) 2 cleaves Ang‐II into the vasodilator
peptide Ang‐(1–7), thus acting as a pivotal element in balancing the local effects of these …

Hypertension is one of the cardiovascular diseases that might cause cardiovascular
remodeling and endothelial dysfunction besides high blood pressure. Angiotensin II (Ang II) …

Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing
data from animal model, epidemiological, and genomic studies that commonly used …

Abstract Purpose of Review In many instances, the renin-angiotensin system (RAS) and the
vasopressinergic system (VPS) are jointly activated by the same stimuli and engaged in the …

Current experimental stroke research has evolved to focus on detailed understanding of the
brain's self-protective and restorative mechanisms, and harness this knowledge for …

In this study, we provide evidence for the first time that membrane‐bound endopeptidase
neurolysin is up‐regulated in different parts of mouse brain affected by focal ischemia …

The renin-angiotensin system (RAS) and its active peptide angiotensin II (AngII) have major
involvements not only in hypertension but also in mood and anxiety disorders. Substantial …

Recently, we discovered a novel non-angiotensin type 1 (non-AT 1), non-AT 2 angiotensin
binding site in rodent and human brain membranes, which is distinctly different from …

A relationship between the central renin angiotensin system and the dopaminergic system
has been described in the striatum. However, the role of the angiotensin II type 2 (AT2) …

The rostral ventrolateral medulla (RVLM) and the presympathetic bulbospinal neurons in
this region play a critical role in cardiovascular regulation. However, there is ambiguity …