The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …

The endothelium, although only a single layer of cells lining the vascular and lymphatic
systems, contributes in multiple ways to vascular homeostasis. Subsequent to the 1980 …

Of the 21 members of the connexin family, 4 (Cx37, Cx40, Cx43, and Cx45) are expressed in
the endothelium and/or smooth muscle of intact blood vessels to a variable and dynamically …

Inflammatory arterial diseases differentially affect the compartments of the vessel wall. The
intima and adventitia are commonly involved by the disease process, with luminal and …

Background: Spontaneous deep intracerebral hemorrhage (ICH) is a devastating subtype of
stroke without specific treatments. It has been thought that smooth muscle cell (SMC) …

Arterioles are the blood vessels in the arterial side of the vascular tree that are located
proximal to the capillaries and, in conjunction with the terminal arteries, provide the majority …

It is becoming increasingly evident that electrical signaling via gap junctions plays a central
role in the physiological control of vascular tone via two related mechanisms (1) the …

Cells present in the adventitia, or outermost layer of the blood vessel, contribute to the
progression of vascular diseases, such as atherosclerosis, hypertension, and aortic …

Over the past 66 years, our knowledge of the role of the endothelium in the regulation of
cardiovascular function and dysfunction has advanced from the assumption that it is a single …

Epidemiological studies demonstrate that there are sex differences in the incidence,
prevalence, and outcomes of cerebrovascular disease (CVD). The present study compared …