The collection of components required to carry out the intricate processes involved in
generating and maintaining a living, breathing and, sometimes, thinking organism is …

Chromatin immunoprecipitation followed by sequencing (ChIP–seq) is a technique for
genome-wide profiling of DNA-binding proteins, histone modifications or nucleosomes …

Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex
systems. However, a comprehensive single-cell atlas has not been achieved for humans …

While genome assembly projects have been successful in many haploid and inbred
species, the assembly of noninbred or rearranged heterozygous genomes remains a major …

Abstract The Encyclopedia of DNA Elements (ENCODE) is an ongoing collaborative
research project aimed at identifying all the functional elements in the human and mouse …

Abstract miRBase is the primary online repository for all microRNA sequences and
annotation. The current release (miRBase 16) contains over 15 000 microRNA gene loci in …

Chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-
seq) has become a valuable and widely used approach for map** the genomic location of …

Abstract The Saccharomyces Genome Database (SGD, http://www. yeastgenome. org) is the
community resource for the budding yeast Saccharomyces cerevisiae. The SGD project …

Despite an abundance of new studies about topologically associating domains (TADs), the
role of genetic information in TAD formation is still not fully understood. Here we use our …

Drosophila melanogaster is one of the most well studied genetic model organisms;
nonetheless, its genome still contains unannotated coding and non-coding genes …