Harnessing nanomaterials for cancer sonodynamic immunotherapy
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …
However, such emerging therapy still suffers from the low response rates and immune …
Recent advances in nanomaterial‐assisted combinational sonodynamic cancer therapy
Ultrasound (US)‐triggered sonodynamic therapy (SDT), as a promising noninvasive
therapeutic modality, has received ever‐increasing attention in recent years. Its specialized …
therapeutic modality, has received ever‐increasing attention in recent years. Its specialized …
Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer
Nanomedicine in combination with immunotherapy offers opportunities to treat cancer in a
safe and effective manner; however, remote control of immune response with spatiotemporal …
safe and effective manner; however, remote control of immune response with spatiotemporal …
A nitric-oxide driven chemotactic nanomotor for enhanced immunotherapy of glioblastoma
H Chen, T Li, Z Liu, S Tang, J Tong, Y Tao… - Nature …, 2023 - nature.com
The major challenges of immunotherapy for glioblastoma are that drugs cannot target tumor
sites accurately and properly activate complex immune responses. Herein, we design and …
sites accurately and properly activate complex immune responses. Herein, we design and …
Biomineralized MnO2 Nanoplatforms Mediated Delivery of Immune Checkpoint Inhibitors with STING Pathway Activation to Potentiate Cancer Radio-Immunotherapy
Radiotherapy (RT), as one of the main methods in the clinical treatment of various malignant
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
tumors, would induce systemic immunotherapeutic effects by triggering immunogenic cell …
Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2, 3-dioxygenase-blockade tumor immunotherapy
L Dai, M Yao, Z Fu, X Li, X Zheng, S Meng… - Nature …, 2022 - nature.com
Inhibited immune response and low levels of delivery restrict starvation cancer therapy
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
A “closed‐loop” therapeutic strategy based on mutually reinforced ferroptosis and immunotherapy
Y Du, R Zhang, J Yang, S Liu, J Zhou… - Advanced Functional …, 2022 - Wiley Online Library
The immunosuppression and immune escape of current immunotherapy result in low
efficacy, and ferroptosis is greatly restricted by the low reactive oxygen species (ROS) …
efficacy, and ferroptosis is greatly restricted by the low reactive oxygen species (ROS) …
Advances in metal–organic framework-based nanozymes and their applications
X Huang, S Zhang, Y Tang, X Zhang, Y Bai… - Coordination Chemistry …, 2021 - Elsevier
Nanozymes bridge the fields of inorganic nanomaterials and biology and have attracted
wide attention. Nanozymes have the catalytic capabilities of inorganic materials at the …
wide attention. Nanozymes have the catalytic capabilities of inorganic materials at the …
Nanoparticle‐mediated radiotherapy remodels the tumor microenvironment to enhance antitumor efficacy
Radiotherapy (RT) uses ionizing radiation to eradicate localized tumors and, in rare cases,
control tumors outside of the irradiated fields via stimulating an antitumor immune response …
control tumors outside of the irradiated fields via stimulating an antitumor immune response …
Boosting checkpoint immunotherapy with biomaterials
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …