Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has
become available such that the 2003 consensus statement requires revision and update …

Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors
in the world. The incidence of HCC varies considerably with the geographic area because of …

Background: Identifying risk factors for the development of complications of chronic hepatitis
B (CHB) is important for setting up treatment criteria. Aim: To determine risk factors for the …

BACKGROUND/AIMS: The long-term outcomes of interferon-alpha (IFN-α) therapy in
hepatitis B e antigen (HBeAg) seropositive patients remain controversial. This study was …

Background & aims: Increased morbidity and mortality from liver disease have been
reported in chronic hepatitis B surface antigen (HBsAg) carriers, but data on survival are …

Background & Aims: Chronic hepatitis B is an important public health problem worldwide
and in the United States. A treatment algorithm for chronic hepatitis B virus (HBV) infection …

Although chronic HBV infection is the leading cause of chronic liver disease and death
worldwide, there are substantial differences in its clinical courses regarding prevalence …

BACKGROUND & AIMS: Some patients with chronic hepatitis B virus (HBV) infection
progress to hepatocellular carcinoma (HCC). However, the long-term effect of nucleos (t) ide …

The baseline alanine aminotransferase (ALT) level was reported to have prognostic value in
chronic hepatitis B virus (HBV) infection, during which ALT may change over time. Instead of …

CD4+ T cells are thought to contribute to antiviral immune responses by secretion of
cytokines thereby providing help to CD8+ T and B cells. However, perforin‐positive cytotoxic …