Nutrigenomics, rumen-derived bioactive fatty acids, and the regulation of milk fat synthesis

DE Bauman, KJ Harvatine, AL Lock - Annual review of nutrition, 2011 - annualreviews.org
Mammary synthesis of milk fat continues to be an active research area, with significant
advances in the regulation of lipid synthesis by bioactive fatty acids (FAs). The …

[HTML][HTML] Induction of and recovery from milk fat depression occurs progressively in dairy cows switched between diets that differ in fiber and oil concentration

DE Rico, KJ Harvatine - Journal of Dairy Science, 2013 - Elsevier
Milk fat depression (MFD) caused by intermediates of ruminal biohydrogenation commonly
occurs in dairy cattle. The time course of recovery from MFD is important to mechanistic …

[HTML][HTML] Milk protein synthesis in the lactating mammary gland: Insights from transcriptomics analyses

M Bionaz, W Hurley, J Loor - Milk protein, 2012 - intechopen.com
In recent years, and with the advent of more advanced molecular techniques, a compelling
case has been made for more in-depth studies of molecular regulation of lactation …

[HTML][HTML] Effect of conjugated linoleic acid supplementation on body composition, body fat mobilization, protein accretion, and energy utilization in early lactation dairy …

D Von Soosten, U Meyer, M Piechotta… - Journal of Dairy …, 2012 - Elsevier
The objective of the study was to investigate the effects of trans-10, cis-12 and cis-9, trans-11
conjugated linoleic acid (CLA) supplementation on body composition, mobilization or …

[HTML][HTML] Lipid complex effect on fatty acid profile and chemical composition of cow milk and cheese

R Bodkowski, K Czyż, R Kupczyński… - Journal of Dairy …, 2016 - Elsevier
The effect of administration of lipid complex (LC) on cow milk and cheese characteristics
was studied. Lipid complex was elaborated based on grapeseed oil with synthesized …

[HTML][HTML] A canonical discriminant analysis to study the association between milk fatty acids of ruminal origin and milk fat depression in dairy cows

G Conte, C Dimauro, A Serra, NPP Macciotta… - Journal of Dairy …, 2018 - Elsevier
Although milk fat depression (MFD) has been observed and described since the beginning
of the last century, all the molecular and biochemical mechanisms involved are still not …

[HTML][HTML] Effects of a rumen-protected mixture of conjugated linoleic acids on hepatic expression of genes involved in lipid metabolism in dairy cows

G Schlegel, R Ringseis, W Windisch, FJ Schwarz… - Journal of dairy …, 2012 - Elsevier
Supplementation of conjugated linoleic acids (CLA) reduces milk fat content in dairy cows
and, thus, may be a useful dietary strategy to improve energy balance during early lactation …

A rumen unprotected conjugated linoleic acid supplement inhibits milk fat synthesis and improves energy balance in lactating goats

M Baldin, MAS Gama, R Dresch… - Journal of Animal …, 2013 - academic.oup.com
Abstract Feeding trans-10, cis-12 CLA supplements in a rumen-protected form has been
shown to cause milk fat depression (MFD) in cows, ewes, and goats. Methyl esters of CLA …

[HTML][HTML] The effect of dietary rumen-protected trans-10, cis-12 conjugated linoleic acid or a milk fat-depressing diet on energy metabolism, inflammation, and oxidative …

AR Bayat, A Razzaghi, M Sari, P Kairenius… - Journal of Dairy …, 2022 - Elsevier
The objective of this study was to determine the effects of milk fat depression induced by
supplementing conjugated linoleic acid (CLA; trans-10, cis-12 and cis-9, trans-11 CLA) or …

Peroxisome proliferator-activated receptor gamma (PPARγ) agonist fails to overcome trans-10, cis-12 conjugated linoleic acid (CLA) inhibition of milk fat in dairy …

EC Sandri, M Camêra, EM Sandri, KJ Harvatine… - Animal, 2018 - cambridge.org
The trans-10, cis-12 conjugated linoleic acid (CLA) causes milk fat depression by
downregulating expression of genes and transcription factors involved in lipogenesis and it …