Tumors are one of the main causes of death in humans. The development of safe and
effective methods for early diagnosis and treatment of tumors is a difficult problem that needs …

Globally, clear-cell renal cell carcinoma (ccRCC) represents the most prevalent type of
kidney cancer. Surgery plays a key role in the treatment of this cancer, although one third of …

Clear cell renal cell carcinoma (ccRCC) is one of the most immunologically distinct tumor
types due to high response rate to immunotherapies, despite low tumor mutational burden …

The crosstalk among the complement system, immune cells, and mediators of inflammation
provides an efficient mechanism to protect the organism against infections and support the …

Background Chemokine (CXC motif) ligand 13 (CXCL13) was known as a selective
chemotaxis for B cells, a product of follicular helper CD4+ T cells (TFH) and a contributor to …

Simple Summary Scientists around the world have long been interested in understanding
the biology of cancer. Numerous studies that have been carried out so far clearly show that …

Background Clear cell renal cell carcinoma is susceptible to ferroptosis, and immunotherapy
is recently recommended as a priority for the initial treatment of metastatic clear cell renal …

Simple Summary Clear cell renal cell carcinomas (ccRCC) have several distinct
immunological features, including a high degree of immune infiltration and relatively low …

Background Patients with clear cell renal cell carcinoma (ccRCC) with venous tumor
thrombus have a poor prognosis, high surgical risk, and lack of targeted therapeutic agents …

Clear cell renal cell carcinoma (ccRCC) presents a unique profile characterized by high
levels of angiogenesis and robust vascularization. Understanding the underlying …