Histotripsy: the first noninvasive, non-ionizing, non-thermal ablation technique based on ultrasound

Z Xu, TL Hall, E Vlaisavljevich… - International Journal of …, 2021 - Taylor & Francis
Histotripsy is the first noninvasive, non-ionizing, and non-thermal ablation technology
guided by real-time imaging. Using focused ultrasound delivered from outside the body …

Histotripsy: a method for mechanical tissue ablation with ultrasound

Z Xu, TD Khokhlova, CS Cho… - Annual Review of …, 2024 - annualreviews.org
Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy
tissue into subcellular debris using high-amplitude focused ultrasound pulses. In contrast to …

[HTML][HTML] For whom the bubble grows: physical principles of bubble nucleation and dynamics in histotripsy ultrasound therapy

KB Bader, E Vlaisavljevich, AD Maxwell - Ultrasound in medicine & biology, 2019 - Elsevier
Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …

Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications

VA Khokhlova, JB Fowlkes, WW Roberts… - International journal …, 2015 - Taylor & Francis
In high intensity focused ultrasound (HIFU) therapy, an ultrasound beam is focused within
the body to locally affect the targeted site without damaging intervening tissues. The most …

Direct sound printing

M Habibi, S Foroughi, V Karamzadeh… - Nature …, 2022 - nature.com
Photo-and thermo-activated reactions are dominant in Additive Manufacturing (AM)
processes for polymerization or melting/deposition of polymers. However, ultrasound …

Ultrasound in tumor immunotherapy: Current status and future developments

YJ Ho, JP Li, CH Fan, HL Liu, CK Yeh - Journal of Controlled Release, 2020 - Elsevier
Immunotherapy has considerable potential in eliminating cancers by activating the host's
own immune system, while the thermal and mechanical effects of ultrasound have various …

Ultrasound in radiology: from anatomic, functional, molecular imaging to drug delivery and image-guided therapy

AL Klibanov, JA Hossack - Investigative radiology, 2015 - journals.lww.com
During the past decade, ultrasound has expanded medical imaging well beyond the
“traditional” radiology setting: a combination of portability, low cost, and ease of use makes …

Ultrasound Augmented Cancer Immunotherapy

B Liu, Z Feng, X **ang, R Guo, L Ma, B Zhu… - Journal of Materials …, 2024 - pubs.rsc.org
Cancer remains a growing worldwide health problem with the most broadly studied
treatments, in which immunotherapy has made notable advancements during the recent …

Effects of tissue mechanical properties on susceptibility to histotripsy-induced tissue damage

E Vlaisavljevich, Y Kim, G Owens… - Physics in Medicine …, 2013 - iopscience.iop.org
Histotripsy is a non-invasive tissue ablation method capable of fractionating tissue by
controlling acoustic cavitation. To determine the fractionation susceptibility of various …

The histotripsy spectrum: differences and similarities in techniques and instrumentation

RP Williams, JC Simon, VA Khokhlova… - International Journal …, 2023 - Taylor & Francis
Since its inception about two decades ago, histotripsy–a non-thermal mechanical tissue
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …