[HTML][HTML] Beneficial effects of green tea catechins on neurodegenerative diseases

M Pervin, K Unno, T Ohishi, H Tanabe, N Miyoshi… - Molecules, 2018 - mdpi.com
Tea is one of the most consumed beverages in the world. Green tea, black tea, and oolong
tea are made from the same plant Camellia sinensis (L.) O. Kuntze. Among them, green tea …

Amyloid β protein and Alzheimer's disease: When computer simulations complement experimental studies

J Nasica-Labouze, PH Nguyen, F Sterpone… - Chemical …, 2015 - ACS Publications
Alzheimer's disease (AD) challenges our society with an annual estimated cost of $1.08
trillion in the United States alone by 2050. 1 AD is a progressive irreversible neurological …

Polyphenol-binding amyloid fibrils self-assemble into reversible hydrogels with antibacterial activity

B Hu, Y Shen, J Adamcik, P Fischer, M Schneider… - ACS …, 2018 - ACS Publications
Adaptable hydrogel networks with reversible connectivity have emerged as a promising
platform for biomedical applications. Synthetic copolymers and low-molecular-weight …

Structure remodeling of soy protein-derived amyloid fibrils mediated by epigallocatechin-3-gallate

Z Xu, G Shan, N Hao, L Li, T Lan, Y Dong, J Wen… - Biomaterials, 2022 - Elsevier
Soy protein-derived amyloid fibrils (SAFs) held desirable features, and with rational tailoring
of physical structures, their techno-functions could be further improved. Here, we report a …

Natural product-based amyloid inhibitors

P Velander, L Wu, F Henderson, S Zhang… - Biochemical …, 2017 - Elsevier
Many chronic human diseases, including multiple neurodegenerative diseases, are
associated with deleterious protein aggregates, also called protein amyloids. One common …

Amyloid–polyphenol hybrid nanofilaments mitigate colitis and regulate gut microbial dysbiosis

B Hu, S Yu, C Shi, J Gu, Y Shao, Q Chen, Y Li… - ACS …, 2020 - ACS Publications
It is a desirable and powerful strategy to precisely fabricate functional soft matter through self-
assembly of molecular building blocks across a range of length scales. Proteins, nucleic …

Green Tea Extracts EGCG and EGC Display Distinct Mechanisms in Disrupting Aβ42 Protofibril

C Zhan, Y Chen, Y Tang, G Wei - ACS chemical neuroscience, 2020 - ACS Publications
The amyloid beta (Aβ) fibrillar aggregate is the hallmark of Alzheimer's disease (AD).
Disassembling preformed fibril or inhibiting Aβ aggregation is considered as a therapeutic …

[HTML][HTML] Multifaceted neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) in Alzheimer's disease: An overview of pre-clinical studies focused on β-amyloid …

K Youn, CT Ho, M Jun - Food Science and Human Wellness, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
cognitive decline and memory impairment. Many lines of evidence indicate that excessive β …

Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases

B Cheng, H Gong, H **ao, RB Petersen… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Background The deposition of self-assembled amyloidogenic proteins is associated with
multiple diseases, including Alzheimer's disease, Parkinson's disease and type 2 diabetes …

Dietary polyphenols as therapeutic intervention for Alzheimer's disease: a mechanistic insight

SNA Bukhari - Antioxidants, 2022 - mdpi.com
Dietary polyphenols encompass a diverse range of secondary metabolites found in nature,
such as fruits, vegetables, herbal teas, wine, and cocoa products, etc. Structurally, they are …