Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

St. Johnʼs wort (Hypericum perforatum) has been intensively investigated for its
antidepressive activity, but dermatological applications also have a long tradition. Topical St …

Spirulina is a well-described and popular dietary supplement derived from Arthrospira
algae. In the present study, the anticancer potential of a water extract of a commercial …

Abstract Hypericum perforatum L.(Clusiaceae), commonly known as St. John's wort, has a
rich historical background as one of the oldest and most widely studied herbal medicines …

Acute myeloid leukemia (AML) is a hematological malignancy characterized by a rapid
increase in the number of immature myeloid cells in bone marrow. Despite recent advances …

In this paper we review the mechanisms of the antitumor effects of Hypericum perforatum
L.(St. John's wort, SJW) and its main active component hyperforin (HPF). SJW extract is …

Traditional herbal medicine (THM) is a “core” from which modern medicine has evolved over
time. Besides this, one third of people worldwide have no access to modern medicine and …

Hyperforin (HPF), the main component responsible for the antidepressant action of
Hypericum perforatum, displays additional beneficial properties including anti-inflammatory …

Background An increasing number of studies have revealed the influencing factors of
ferroptosis. The influence of immune cell infiltration, inflammation development and lipid …

Akt kinase is a serine threonine kinase that exists in three isoforms, located in different
chromosomes and has distinct sites of expression which orchestrates diverse cellular …