Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

GH Goossens, JWE Jocken, EE Blaak - Nature Reviews Endocrinology, 2021 - nature.com
Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

The role of adipose tissue in cardiovascular health and disease

EK Oikonomou, C Antoniades - Nature Reviews Cardiology, 2019 - nature.com
Accumulating knowledge on the biology and function of the adipose tissue has led to a
major shift in our understanding of its role in health and disease. The adipose tissue is now …

Relationships between rodent white adipose fat pads and human white adipose fat depots

DE Chusyd, D Wang, DM Huffman, TR Nagy - Frontiers in nutrition, 2016 - frontiersin.org
The objective of this review was to compare and contrast the physiological and metabolic
profiles of rodent white adipose fat pads with white adipose fat depots in humans. Human fat …

Biology of upper-body and lower-body adipose tissue—link to whole-body phenotypes

F Karpe, KE Pinnick - Nature Reviews Endocrinology, 2015 - nature.com
The distribution of adipose tissue in the body has wide-ranging and reproducible
associations with health and disease. Accumulation of adipose tissue in the upper body …

MicroRNA regulatory networks in human adipose tissue and obesity

P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

Heterogeneity of adipose tissue in development and metabolic function

T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …

[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction

AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

MicroRNAs in obesity and related metabolic disorders

JF Landrier, A Derghal, L Mounien - Cells, 2019 - mdpi.com
Metabolic disorders are characterized by the inability to properly use and/or store energy.
The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through …

Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on …

P Poirier, TD Giles, GA Bray, Y Hong, JS Stern… - Circulation, 2006 - Am Heart Assoc
Obesity is becoming a global epidemic in both children and adults. It is associated with
numerous comorbidities such as cardiovascular diseases (CVD), type 2 diabetes …

Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study

S Yusuf, S Hawken, S Ôunpuu, L Bautista, MG Franzosi… - The Lancet, 2005 - thelancet.com
Background Obesity is a major risk factor for cardiovascular disease, but the most predictive
measure for different ethnic populations is not clear. We aimed to assess whether markers of …