Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …

Macrophages are the gatekeepers of intestinal immune homeostasis as they discriminate
between innocuous antigens and potential pathogens to maintain oral tolerance. However …

Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins
usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of …

The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Resolution of inflammation is a coordinated and active process aimed at restoration of tissue
integrity and function. This review integrates the key molecular and cellular mechanisms of …

Non-resolving inflammation drives the development of clinically dangerous atherosclerotic
lesions by promoting sustained plaque inflammation, large necrotic cores, thin fibrous caps …

The critical role of inflammatory processes in health and disease has long been recognized,
1 yet the detailed molecular mechanisms and biological events that regulate the progression …

Oxylipins formed from polyunsaturated fatty acids (PUFAs) are the main mediators of PUFA
effects in the body. They are formed via cyclooxygenase, lipoxygenase, and cytochrome …

Neutrophils, monocytes and macrophages are closely related phagocytic cells that
cooperate during the onset, progression and resolution of inflammation. This Review …