Although histone acetylases (HDACS) were initially believed to render chromatin in a
transcriptionally repressed state by deacetylating histones, it is now known that they both …

Nephron progenitor cells (NPCs) are Six2-positive metanephric mesenchyme cells, which
undergo self-renewal and differentiation to give rise to nephrons until the end of …

Lipid droplets are found in most organisms where they serve to store energy in the form of
neutral lipids. They are formed at the endoplasmic reticulum (ER) membrane where the …

Histone deacetylases (HDACs) regulate a broad range of biological processes through
removal of acetyl groups from histones as well as non-histone proteins. Our previous studies …

The tumor suppressor protein adenomatous polyposis coli (APC) is multifunctional–it
participates in the canonical Wnt/β-catenin signal transduction pathway as well as …