Recent advances in heterocyclic nanographenes and other polycyclic heteroaromatic compounds

A Borissov, YK Maurya, L Moshniaha… - Chemical …, 2021 - ACS Publications
This review surveys recent progress in the chemistry of polycyclic heteroaromatic molecules
with a focus on structural diversity and synthetic methodology. The article covers literature …

[HTML][HTML] Recent advances on anticancer activity of coumarin derivatives

A Rawat, AVB Reddy - European Journal of Medicinal Chemistry Reports, 2022 - Elsevier
Coumarin derivatives are important class of natural plant metabolites that offer variety of
biological activities. They can also be derived synthetically, and a wide variety of synthetic …

Magnetically active iron oxide nanoparticles for catalysis of organic transformations: a review

P Kumar, V Tomar, D Kumar, RK Joshi, M Nemiwal - Tetrahedron, 2022 - Elsevier
Magnetic iron oxide nanoparticles (MIONPs) are an efficient retrievable catalytic system
recognized for their broad applications in numerous fields, including pharmaceutical …

[HTML][HTML] Therapeutic potential of 4-substituted coumarins: A conspectus

M Sharma, VK Vyas, S Bhatt, MD Ghate - European Journal of Medicinal …, 2022 - Elsevier
Substituted coumarins are a very large family of naturally occurring compounds, and
substituted coumarins are versatile scaffolds for the development of medicinally active …

Novel 3-substituted coumarins inspire a custom pharmacology prediction pipeline: an anticancer discovery adventure

IK Matar, ZA Muhammad, SM Gomha… - Future Medicinal …, 2024 - Taylor & Francis
Aim: This research aims to expand the established pharmacological space of tumor-
associated carbonic anhydrases (TACAs) by exploring the synthetically accessible chemical …

Coumarin as an Elite Scaffold in Anti-Breast Cancer Drug Development: Design Strategies, Mechanistic Insights, and Structure–Activity Relationships

A Singh, K Singh, K Kaur, A Singh, A Sharma, K Kaur… - Biomedicines, 2024 - mdpi.com
Breast cancer is the most common cancer among women. Currently, it poses a significant
threat to the healthcare system due to the emerging resistance and toxicity of available drug …

Novel complexes with ONNO tetradentate coumarin schiff-base donor ligands: x-ray structures, DFT calculations, molecular dynamics and potential anticarcinogenic …

PD Mestizo, DM Narváez, JA Pinzón-Ulloa, DT Di Bello… - BioMetals, 2021 - Springer
The synthesis of eight novel Zn (II), Co (II), Cu (II), Ni (II) and Pt (II) complexes (2–9) derived
from the ONNO tetradentate coumarin Schiff-Base donor ligands, L 1 and the novel L 2, was …

Coumarin–1, 2, 4-triazole hybrids: Recent advances in synthesis and medicinal applications

M Chandrakanth, NM Thomas, CG Arya… - Journal of Molecular …, 2024 - Elsevier
Abstract Coumarin and 1, 2, 4-triazole compounds have been widely used in drug design
and development due to their widespread biological applications. Combination of these two …

DABCO-Promoted Cyclization of 2-Amino-4H-chromen-4-ones with 2,6-Dibenzylidenecyclohexan-1-ones for the Synthesis of Chromeno[2,3-b]tetrahydroquinoline

Y Xue, J Gan, N Luo, C Wang - The Journal of Organic Chemistry, 2022 - ACS Publications
DABCO-promoted cyclization reaction of substituted 2-amino-4 H-chromen-4-ones with
substituted 2, 6-dibenzylidenecyclohexan-1-ones was investigated under mild conditions …

Novel benzo [f] coumarin derivatives as probable acetylcholinesterase inhibitors: synthesis, in vitro, and in silico studies for evaluation of their anti-AChE activity

Z Nabeel, QAH Jaber… - Indonesian Journal of …, 2021 - journal.ugm.ac.id
Novel benzo [f] coumarin derivatives bearing pyrimidine unit were successfully synthesized.
The target is to develop novel acetylcholinesterase inhibitors. The benzo [f] coumarin …