The microvasculature plays a key role in oxygen transport in the mammalian brain. Despite
the close coupling between cerebral vascular geometry and local oxygen demand, recent …

Background Intra-arterial thrombectomy is the main treatment for acute ischemic stroke due
to large vessel occlusions and can consist in mechanically removing the thrombus with a …

Development of therapeutics for brain diseases has remained challenging, in particular due
to the difficulty of passing the blood-brain barrier. As a result, the current arsenal of …

Microglia, the resident immune cells in the central nervous system, can monitor the
microenvironment and actively respond to ischemic stroke and other brain injuries. In this …

Treatment of acute ischemic stroke (AIS) has gained interest in the recent years with the
introduction, first of intravenous administration of thrombus-dissolving drugs, and more …