Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …

Epilepsy is one of the most common neurological chronic disorders, with an estimated
prevalence of 0. 5–1%. Currently, treatment options for epilepsy are predominantly based on …

Objective We evaluated the efficacy and safety of deep brain anterior thalamus stimulation
after 7 and 10 years, and report the incidence of sudden unexpected death in epilepsy …

Objective To prospectively evaluate safety and efficacy of brain-responsive neurostimulation
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …

Abstract The Infectious Diseases Society of America (IDSA) Standards and Practice
Guidelines Committee collaborated with partner organizations to convene a panel of 10 …

Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

Cross-frequency coupling (CFC) reflects (nonlinear) interactions between signals of different
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …

Detection of neural signatures related to pathological behavioral states could enable
adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for …

Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …