MADS-domain transcription factors and the floral quartet model of flower development: linking plant development and evolution
The floral quartet model of floral organ specification poses that different tetramers of MIKC-
type MADS-domain transcription factors control gene expression and hence the identity of …
type MADS-domain transcription factors control gene expression and hence the identity of …
International union of basic and clinical pharmacology CXIII: Nuclear receptor superfamily—Update 2023
The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …
gene network programs involved in a wide range of physiologic processes. This review will …
The forkhead-box family of transcription factors: key molecular players in colorectal cancer pathogenesis
P Laissue - Molecular cancer, 2019 - Springer
Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the
fourth most frequent cause of death having an oncological origin. It has been found that …
fourth most frequent cause of death having an oncological origin. It has been found that …
Forkhead transcription factors in health and disease
Forkhead box (FOX) proteins belong to an evolutionarily conserved family of transcription
factors that has evolved by gene/genome duplication. FOX family members have undergone …
factors that has evolved by gene/genome duplication. FOX family members have undergone …
Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions
Charting a temporal path in gene networks requires linking early transcription factor (TF)-
triggered events to downstream effects. We scale-up a cell-based TF-perturbation assay to …
triggered events to downstream effects. We scale-up a cell-based TF-perturbation assay to …
Complementary strategies for directing in vivo transcription factor binding through DNA binding domains and intrinsically disordered regions
DNA binding domains (DBDs) of transcription factors (TFs) recognize DNA sequence motifs
that are highly abundant in genomes. Within cells, TFs bind a subset of motif-containing sites …
that are highly abundant in genomes. Within cells, TFs bind a subset of motif-containing sites …
The molecular grammar of protein disorder guiding genome-binding locations
F Jonas, M Carmi, B Krupkin, J Steinberger… - Nucleic acids …, 2023 - academic.oup.com
Intrinsically disordered regions (IDRs) direct transcription factors (TFs) towards selected
genomic occurrences of their binding motif, as exemplified by budding yeast's Msn2 …
genomic occurrences of their binding motif, as exemplified by budding yeast's Msn2 …
Retrons and their applications in genome engineering
Precision genome editing technologies have transformed modern biology. These
technologies have arisen from the redirection of natural biological machinery, such as …
technologies have arisen from the redirection of natural biological machinery, such as …
A mouse tissue transcription factor atlas
Q Zhou, M Liu, X **a, T Gong, J Feng, W Liu… - Nature …, 2017 - nature.com
Transcription factors (TFs) drive various biological processes ranging from embryonic
development to carcinogenesis. Here, we employ a recently developed concatenated …
development to carcinogenesis. Here, we employ a recently developed concatenated …
Targeting intrinsically disordered transcription factors: changing the paradigm
Increased understanding of intrinsically disordered proteins (IDPs) and protein regions has
revolutionized our view of the relationship between protein structure and function. Data now …
revolutionized our view of the relationship between protein structure and function. Data now …