Virus-like particles (VLPs) are increasingly used for vaccine development and drug delivery.
Assembly of VLPs from purified monomers in a chemically defined reaction is advantageous …

A significant growth of research in nanofluidics is achieved over the past decade, but the
field is still facing considerable challenges toward the transition from the current physics …

Single-entity (or digital) measurements enhance sensitivity (10-to 100-fold improvement)
and uncover heterogeneity within a population (one event in 100 to 10,000). Many biological …

High-speed tracking of single particles is a gateway to understanding physical, chemical,
and biological processes at the nanoscale. It is also a major experimental challenge …

As analytical interests have become targeted on sensitive detection of objects of a tiny size
and volume, various fields in analytical chemistry have been developed to overcome …

Extracellular vesicles (EVs) are cell-derived, naturally produced, membrane-bound
nanoscale particles that are linked to cell-cell communication and the propagation of …

Viruses have drawn much attention in recent years due to increased recognition of their
important roles in virology, immunology, clinical diagnosis, and therapy. Because the …

Cowpea chlorotic mottle virus (CCMV) is a widely used model for virus replication studies. A
major challenge lies in distinguishing between the roles of the interaction between coat …

The survival of viruses partly relies on their ability to self-assemble inside host cells.
Although coarse-grained simulations have identified different pathways leading to …

Understanding capsid assembly is important because of its role in virus lifecycles and in
applications to drug discovery and nanomaterial development. Many virus capsids are …